Abstract

Resveratrol is a natural polyphenolic compound containing antioxidant property found in red wine, grapes, berries and peanuts. In vitro and in vivo studies suggest that trans-resveratrol is more effective in reducing platelet aggregation, improving endothelial function, inhibiting LDL oxidation and have antiatherogenic properties. However, clinical studies were not conducted nor reported on any beneficial effects on CHD in humans. Resveratrol supplements are available in U.S. markets and they may contain anywhere from 10-50 mg of resveratrol, but the effective doses for chronic disease prevention in humans are not known.

Keywords: Coronary heart disease, resveratrol, cardioprotection