Current Nutrition & Food Science

Author(s): Allam Appa Rao

DOI: 10.2174/157340108785133400

Differential Expression of Genes in Obesity and Type 2 Diabetes Mellitus

Page: [206 - 208] Pages: 3

  • * (Excluding Mailing and Handling)

Abstract

Both obesity and type 2 diabetes mellitus are common. In a gene expression profile study, it was noted that genes concerned with carbohydrate, lipid and amino acid metabolism, and signal transduction pathways are upregulated, while genes involved in cell adhesion, cytokine-cytokine receptor interaction, insulin signaling, immune system pathways, and inflammatory pathway are differentially expressed both in obesity and type 2 diabetes.

Keywords: obesity, type 2 diabetes mellitus, metabolism, cytokine-cytokine receptor interaction, immune system pathways, inflammatory pathway, Carbon reactive protein (CRP)