Abstract

In modern times, individuals are frequently subjected to a wide range of environmental and chemical pollutants that are generated by industrial and agricultural activities. The contamination of food by pesticides, biogenic amines, and mycotoxins represents a significant concern for global food safety, and has economic and public health implications, particularly in newly industrialized nations. A growing body of evidence suggests that prolonged exposure to food contaminants, known as xenobiotics, can have adverse effects on human health. Although many strategies for food decontamination are frequently used, they require specific conditions that are often difficult to meet in many industrial sectors. Currently, a promising strategy for mitigating the potential hazards associated with xenobiotics in food items involves the implementation of a biological detoxification method utilizing probiotic strains and their corresponding enzymes. Numerous investigations have corroborated the efficacy, practicality, and cost-effectiveness of postbiotics in impeding xenobiotic-induced dysbiosis and mitigating their toxicological effects. This review aims to summarize the current knowledge of the direct mechanisms by which postbiotics can influence the detoxification of xenobiotics. Moreover, the effects of postbiotics on host response to exposure to xenobiotics were discussed.

Keywords: Xenobiotic, probiotic, postbiotic, food safety.