Background: One of the oldest known edible fruits, the pomegranate (Punica granatum L.), is now widely consumed worldwide. Its fruits and seed are rich in many bioactive compounds, such as polyphenols, and the scientific interest in this plant has been constantly growing in recent years.
Introduction: Pomegranate fruit and its juice have been shown to have health benefits relating to their antioxidant and anti-inflammatory properties. They are used in alternative medicine as adaptogens and ergogens, protecting against many neurological, cardiovascular, gastrointestinal, liver, and skin disorders.
Methods: Given the amount of evidence, this narrative review does not seek to supply a comprehensive summary of all study findings but rather focuses on human clinical trials related to the last five years. In this regard, we have performed a check in MEDLINE, and clinical trials presented in this time are summarized.
Results: Pomegranate consumption as a table fruit or juice, which is high in polyphenols, is thus recommended in human diet for its health benefits.The consumption of pomegranate fruit symbolizes a promising therapeutic approach to avert many chronic syndromes.
Conclusion: The findings highlight the need for bigger, more thoroughly planned human clinical trials to continue research into the potential particular effects of pomegranate fruit, as well as to determine the ideal dose and duration of pomegranate juice supplementation.
Keywords: Pomegranate, polyphenols, oxidative stress, antioxidant, clinical trials, human health, performance.