Current Nutrition & Food Science

Author(s): Shashi Soni, Uroosa Noor and Ena Gupta*

DOI: 10.2174/1573401317666210906140254

Impact of Nutrition in the Management of Nutritional Status of Covid-19 Patients

Page: [42 - 53] Pages: 12

  • * (Excluding Mailing and Handling)

Abstract

Abstract: The second outbreak of severe acute respiratory syndrome coronavirus (SARS-CoV-2) is of great concern due to its awful mortality and morbidity rate with decreasing nutritional status and poor lifestyle as well as noteworthy food crisis and affected economy of the world. Increasing food prices, food crisis, global hunger and decreasing availability and feasibility of food are the foremost causes of decreasing nutritional status, which increases the risk of susceptibility to infection and, in turn, leads to unfavorable outcomes of the diseases. Although, in times of the Covid- 19 pandemic, nutrition is of potential attention, and there is a requirement for more exploration in the field of nutrition for the prevention of diseases arising from coronavirus infection. Elderly and individuals with co-morbidity, such as respiratory diseases, cardiovascular diseases, diabetes mellitus and metabolic diseases, are more prone towards getting infected with the coronavirus. Good nutrition is mandatory for healthy immune responses, which can be improved by the inclusion of vitamin A, B6, B12, C, D, E, zinc, selenium, iron, copper and an antioxidant-rich diet.

Keywords: SARS-CoV-2, immune response, co-morbidity, mortality, good nutrition, phytochemicals.

Graphical Abstract

[1]
Ayseli YI, Aytekin N, Buyukkayhan D, Aslan I, Ayseli MT. Food policy, nutrition and nutraceuticals in the prevention and management of COVID-19: Advice for healthcare professionals. Trends Food Sci Technol 2020; 105(105): 186-99.
[http://dx.doi.org/10.1016/j.tifs.2020.09.001] [PMID: 33519086]
[2]
Mishra N, Singh P. Introduction to food microbiology. 1st ed. New Delhi: Kitabmahal 2019.
[3]
Naja F, Hamadeh R. Nutrition amid the COVID-19 pandemic: A multi-level framework for action. Eur J Clin Nutr 2020; 74(8): 1117-21.
[http://dx.doi.org/10.1038/s41430-020-0634-3] [PMID: 32313188]
[4]
Paraiso IL, Revel JS, Stevens JF. Potential use of polyphenols in the battle against COVID-19. Curr Opin Food Sci 2020; 32: 149-55.
[http://dx.doi.org/10.1016/j.cofs.2020.08.004] [PMID: 32923374]
[5]
Law S, Leung AW, Xu C. Is the traditional Chinese herb “Artemisia annua” possible to fight against COVID-19? Integr Med Res 2020; 9(2020) 100474.
[6]
King J, Kosinski-Collins M, Sundberg E. Coronavirus structure, vaccine and therapy development 2020. [cited 2021]. Available from: https://www.biophysics.org/blog/coronavirus-structure-vaccine-and-therapy-development
[7]
Silverio R, Gonçalves DC, Andrade MF, Seelaender M. Coronavirus disease 2019 (COVID-19) and nutritional status: The missing link? Adv Nutr 2020; 00: 1-11.
[http://dx.doi.org/10.1093/advances/nmaa125] [PMID: 32975565]
[8]
Abdulah DM, Hassan AB. Relation of dietary factors with infection and mortality rates of COVID-19 across the World. J Nutr Health Aging 2020; 24(9): 1011-8.
[http://dx.doi.org/10.1007/s12603-020-1512-3] [PMID: 33155630]
[9]
Morens DM, Breman JG, Calisher CH, et al. The origin of COVID-19 and why it matters. Am J Trop Med Hyg 2020; 103(3): 955-9.
[http://dx.doi.org/10.4269/ajtmh.20-0849] [PMID: 32700664]
[10]
Zhang T, Wu Q, Zhang Z. Probable pangolin origin of SARS-CoV-2 associated with the COVID-19 outbreak. Curr Biol 2020; 30(7): 1346-1351.e2.
[http://dx.doi.org/10.1016/j.cub.2020.03.022] [PMID: 32197085]
[11]
Dey SK, Rahman MM, Siddiqi UR, Howlader A. Analyzing the epidemiological outbreak of COVID-19: A visual exploratory data analysis approach. J Med Virol 2020; 92(6): 632-8.
[http://dx.doi.org/10.1002/jmv.25743] [PMID: 32124990]
[12]
Manzanares W, Moreira E, Hardy G. Pharmaconutrition Revisited for Critically ill Covid-19 Patients: Does Selenium Have a Place? Nutrition 2020. [Ahead of print].
[http://dx.doi.org/10.1016/j.nut.2020.110989] [PMID: 33049573]
[13]
Alwarawrah Y, Kiernan K, MacIver NJ. Changes in nutritional status impact immune cell metabolism and function. Front Immunol 2018; 9: 1055.
[http://dx.doi.org/10.3389/fimmu.2018.01055] [PMID: 29868016]
[14]
World Health Organization (WHO). WHO Coronavirus Disease (COVID-19) Dashboard 2020. Available from: https://covid19.who.int/region/searo/country/in(Accessed October 16, 2020).
[15]
Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): A review. JAMA 2020; 324(8): 782-93.
[http://dx.doi.org/10.1001/jama.2020.12839] [PMID: 32648899]
[16]
Ghosh R, Chakraborty A, Biswas A, Chowdhuri S. Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors–an in silico docking and molecular dynamics simulation study. J Biomol Struct Dyn 2020; 1-3.
[PMID: 32568613]
[17]
Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal 2020; 10(2): 102-8.
[http://dx.doi.org/10.1016/j.jpha.2020.03.001] [PMID: 32282863]
[18]
Gupta A, Madhavan MV, Sehgal K, et al. Extrapulmonary manifestations of COVID-19. Nat Med 2020; 26(7): 1017-32.
[http://dx.doi.org/10.1038/s41591-020-0968-3] [PMID: 32651579]
[19]
Jin Y, Yang H, Ji W, et al. Virology, epidemiology, pathogenesis, and control of COVID-19. Viruses 2020; 12(4): 372.
[http://dx.doi.org/10.3390/v12040372] [PMID: 32230900]
[20]
Mirzaie A, Halaji M, Dehkordi FS, Ranjbar R, Noorbazargan H. A narrative literature review on traditional medicine options for treatment of corona virus disease 2019 (COVID-19). Complement Ther Clin Pract 2020; 40101214
[http://dx.doi.org/10.1016/j.ctcp.2020.101214] [PMID: 32891290]
[21]
Xu Z, Shi L, Wang Y, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med 2020; 8(4): 420-2.
[http://dx.doi.org/10.1016/S2213-2600(20)30076-X] [PMID: 32085846]
[22]
Mason RJ. Pathogenesis of COVID-19 from a cell biology perspective. Eur Respir J 2020; 55(4)2000607
[http://dx.doi.org/10.1183/13993003.00607-2020] [PMID: 32269085]
[23]
Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109102433
[http://dx.doi.org/10.1016/j.jaut.2020.102433] [PMID: 32113704]
[24]
Singhal T. A review of coronavirus disease-2019 (COVID-19). Indian J Pediatr 2020; 87(4): 281-6.
[http://dx.doi.org/10.1007/s12098-020-03263-6] [PMID: 32166607]
[25]
WHO What are the symptoms of COVID-19 2020. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/q-a-coronaviruses#:~:text=symptoms (Accessed October, 16, 2020).
[26]
Zu ZY, Jiang MD, Xu PP, et al. Coronavirus disease 2019 (COVID-19): A perspective from China. Radiology 2020; 296(2): E15-25.
[http://dx.doi.org/10.1148/radiol.2020200490] [PMID: 32083985]
[27]
Chand V. Nutrition as a key weapon in strengthening immune system relative to pandemic novel coronavirus disease (COVID-19): A review. Int J Health Sci Res 2020; 10(8): 96-104.
[28]
Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. J Med Virol 2020; 92(5): 479-90.
[http://dx.doi.org/10.1002/jmv.25707] [PMID: 32052466]
[29]
Gombart AF, Pierre A, Maggini S. A review of micronutrients and the immune System–Working in harmony to reduce the risk of infection. Nutrients 2020; 12(1): 236.
[http://dx.doi.org/10.3390/nu12010236] [PMID: 31963293]
[30]
McAuliffe S, Ray S, Fallon E, Bradfield J, Eden T, Kohlmeier M. Dietary micronutrients in the wake of COVID-19: An appraisal of evidence with a focus on high-risk groups and preventative healthcare. BMJ Nutrition, Prevention & Health 2020 2020.
[31]
Richardson DP, Lovegrove JA. Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: A UK perspective. Br J Nutr 2020; 1-7.
[PMID: 32815493]
[32]
Srilakshmi B. Nutrition Science. 4th ed. New Delhi: New Age International Publishers 2014; pp. 256-7.
[33]
Razdan K, Singh K, Singh D. Vitamin D Levels and COVID-19 Susceptibility: Is there any Correlation?. Med Drug Discov 2020; p. 100051.
[34]
Im JH, Je YS, Baek J, Chung MH, Kwon HY, Lee JS. Nutritional status of patients with COVID-19. Int J Infect Dis 2020; 100: 390-3.
[http://dx.doi.org/10.1016/j.ijid.2020.08.018] [PMID: 32795605]
[35]
Mocchegiani E, Costarelli L, Giacconi R, et al. Vitamin E-gene interactions in aging and inflammatory age-related diseases: Implications for treatment. A systematic review. Ageing Res Rev 2014; 14: 81-101.
[http://dx.doi.org/10.1016/j.arr.2014.01.001] [PMID: 24418256]
[36]
Lee GY, Han SN. The role of vitamin E in immunity. Nutrients 2018; 10(11): 1614.
[http://dx.doi.org/10.3390/nu10111614] [PMID: 30388871]
[37]
Hunter J, Arentz S, Goldenberg J, et al. Rapid review protocol: Zinc for the prevention or treatment of COVID-19 and other coronavirus-related respiratory tract infections. Integr Med Res 2020; 9(3)100457
[http://dx.doi.org/10.1016/j.imr.2020.100457] [PMID: 32690999]
[38]
Zhang J, Zhang Y, Huo S, et al. Emotional eating in pregnant women during the COVID-19 pandemic and its association with dietary intake and gestational weight gain. Nutrients 2020; 12(8): 2250.
[http://dx.doi.org/10.3390/nu12082250] [PMID: 32731389]
[39]
Roberton T, Carter ED, Chou VB, et al. Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: A modelling study. Lancet Glob Health 2020; 8(7): e901-8.
[http://dx.doi.org/10.1016/S2214-109X(20)30229-1] [PMID: 32405459]
[40]
Headey DD, Cho A, Goudet S, Oketch JA, Oo TZ. The impacts of the COVID-19 crisis on maternal and child malnutrition in Myanmar: What to expect, and how to protect. Intl Food Policy Res Inst 2020.
[41]
Matsungo TM, Chopera P. The effect of the COVID-19 induced lockdown on nutrition, health and lifestyle patterns among adults in Zimbabwe medRxiv 2020.
[http://dx.doi.org/10.1101/2020.06.16.20130278]
[42]
Wang X, Lei SM, Le S, et al. Bidirectional influence of the COVID-19 pandemic lockdowns on health behaviors and quality of life among chinese adults. Int J Environ Res Public Health 2020; 17(15): 5575.
[http://dx.doi.org/10.3390/ijerph17155575] [PMID: 32748825]
[43]
Pellegrini M, Ponzo V, Rosato R, et al. Changes in weight and nutritional habits in adults with obesity during the “lockdown” period caused by the COVID-19 virus emergency. Nutrients 2020; 12(7): 2016.
[http://dx.doi.org/10.3390/nu12072016] [PMID: 32645970]
[44]
Azzolino D, Saporiti E, Proietti M, Cesari M. Nutritional Considerations in Frail Older Patients with COVID-19. J Nutr Health Aging 2020; 24(7): 696-8.
[http://dx.doi.org/10.1007/s12603-020-1400-x] [PMID: 32744563]
[45]
Radwan E, Radwan A, Radwan W. Challenges Facing Older Adults during the COVID-19 Outbreak. Eur J Environ Public Health 2020; 5(1) em0059.
[http://dx.doi.org/10.29333/ejeph/8457]
[46]
Zhao Q, Meng M, Kumar R, et al. The impact of COPD and smoking history on the severity of COVID-19: A systemic review and meta-analysis. J Med Virol 2020; 92(10): 1915-21.
[http://dx.doi.org/10.1002/jmv.25889] [PMID: 32293753]
[47]
Salleh MR. Life event, stress and illness. Malays J Med Sci 2008; 15(4): 9-18.
[PMID: 22589633]
[48]
Join IF, Calendar P. Boosting immunity: Functional medicine tips on prevention & immunity boosting during the COVID-19 (Coronavirus) outbreak. The Institute for Functional Medicine 2020.
[49]
Simpson RJ, Katsanis E. The immunological case for staying active during the COVID-19 pandemic. Brain Behav Immun 2020; 87: 6-7.
[http://dx.doi.org/10.1016/j.bbi.2020.04.041] [PMID: 32311497]
[50]
Kamdar BB, Needham DM, Collop NA. Sleep deprivation in critical illness: its role in physical and psychological recovery. J Intensive Care Med 2012; 27(2): 97-111.
[http://dx.doi.org/10.1177/0885066610394322] [PMID: 21220271]
[51]
Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch 2012; 463(1): 121-37.
[http://dx.doi.org/10.1007/s00424-011-1044-0] [PMID: 22071480]
[52]
Erol A. High-dose intravenous vitamin C treatment for COVID-19 OSF Preprints 2020. [Ahead of print].
[http://dx.doi.org/10.31219/osf.io/p7ex8]
[53]
Laviano A, Koverech A, Zanetti M. Nutrition support in the time of SARS-CoV-2 (COVID-19). Nutrition 2020; 74110834
[http://dx.doi.org/10.1016/j.nut.2020.110834] [PMID: 32276799]
[54]
Muscogiuri G, Barrea L, Savastano S, Colao A. Nutritional recommendations for CoVID-19 quarantine. Eur J Clin Nutr 2020; 74(6): 850-1.
[http://dx.doi.org/10.1038/s41430-020-0635-2] [PMID: 32286533]
[55]
Inciardi RM, Lupi L, Zaccone G, et al. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19). JAMA Cardiol 2020; 5(7): 819-24.
[http://dx.doi.org/10.1001/jamacardio.2020.1096] [PMID: 32219357]