Search Result "ROC-GTPase"


The Small GTPase Activity of the ROC Domain from LRRK2, a Parkinsons Disease Related Protein

Journal: Protein & Peptide Letters
Volume: 16 Issue: 1 Year: 2009 Page: 1442-1446
Author(s): Qing-Shan Fu, Ai-Xin Song, Su-Xia Li, Hong-Yu Hu

Research Article

Chemical IN04 Inhibits the Kinase Domain not the ROC Domain of LRRK1: Results from Homology Modeling and Molecular Docking

Journal: Medicinal Chemistry
Volume: 17 Issue: 10 Year: 2021 Page: 1140-1150
Author(s): Zhenhang Chen,Weirong Xing,Li Fan

Kinases as Targets for Parkinsons Disease: From Genetics to Therapy

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 10 Issue: 6 Year: 2011 Page: 724-740
Author(s): Renee Vancraenenbroeck, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Jean-Marc Taymans

LRRK2 Kinase Inhibition as a Therapeutic Strategy for Parkinson’s Disease, Where Do We Stand?

Journal: Current Neuropharmacology
Volume: 14 Issue: 3 Year: 2016 Page: 214-225
Author(s): Jean-Marc Taymans,Elisa Greggio

Review Article

LRRK2 and Parkinson's Disease: From Lack of Structure to Gain of Function

Journal: Current Protein & Peptide Science
Volume: 18 Issue: 7 Year: 2017 Page: 677-686
Author(s): Marian Blanca Ramirez,Jesus Madero-Perez,Pilar Rivero-Rios,Mar Martinez-Salvador,Antonio J. Lara Ordonez,Belen Fernandez,Elena Fdez,Sabine Hilfiker

Review Article

Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors:Therapeutic Targets in Atherosclerosis

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 22 Issue: 12 Year: 2022 Page: 1191-1200
Author(s): Jawahar Lal Mehta

Progressive Experimental Screening Tools and Techniques for Parkinsons Disease: An Update

Ebook: Animal Models for Neurological Disorders
Volume: 1 Year: 2021
Author(s): Anil Kumar,Monika Kadian,Hemprabha Tainguriya,Nitin Rawat
Doi: 10.2174/9789815039689121010007

Affinity Can have Many Faces: Thermodynamic and Kinetic Properties of Ras-Effector Complex Formation

Journal: Current Chemical Biology
Volume: 1 Issue: 2 Year: 2007 Page: 215-225
Author(s): Christina Kiel, Luis Serrano

Intra - and Intercellular Calcium Handling in Pulmonary Arterial Hypertension

Journal: Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2016 Page: 162-169
Author(s): Sophia – Anastasia Mouratoglou,George Giannakoulas,Spyridon Deftereos,Georgios Giannopoulos,Christos Angelidis,Michael W. Cleman,Vassilios P. Vassilikos

Transgenic Mouse Models of Parkinsons Disease and Huntingtons Disease

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 9 Issue: 4 Year: 2010 Page: 455-470
Author(s): Stephen D. Skaper, Pietro Giusti

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