Search Result "BACE1 biological properties"


Review Article

An Overview of β-Amyloid Cleaving Enzyme 1 (BACE1) in Alzheimer'sDisease Therapy: Elucidating its Exosite-Binding Antibody andAllosteric Inhibitor

Journal: Current Medicinal Chemistry
Volume: 29 Issue: 1 Year: 2022 Page: 114-135
Author(s): Samuel C. Ugbaja

BACE1 Structure and Function in Health and Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 100-120
Author(s): Sarah L. Cole, Roger Vassar

The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 509-530
Author(s): R. Vassar, S. L. Cole

Biphenyl-Derivatives Possessing Tertiary Amino Groups as β-Secretase (BACE1) Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 7 Year: 2010 Page: 507-515
Author(s): Simone Bertini, Elisa Ghilardi, Valentina Asso, Carlotta Granchi, Filippo Minutolo, Marco Macchia

Discrimination of Active and Weakly Active Human BACE1 Inhibitors Using Self-Organizing Map and Support Vector Machine

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 6 Year: 2016 Page: 470-480
Author(s): Hang Li,Maolin Wang,Ya-Nan Gong,Aixia Yan

Design, Synthesis and In Vitro Biological Evaluation of 3- styrylbenzimidamides as Potential BACE1 Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 4 Year: 2013 Page: 297-302
Author(s): Yan Niu, Haifei Gao, Fengrong Xu, Lei Liang, Peng Liu, Chao Wang, Guanyu Yang, Qi Sun, Ping Xu

Ligand and Structure-Based Drug Design as Strategies for the Screening of New BACE1 Inhibitor Candidates

Journal: Current Physical Chemistry
Volume: 5 Issue: 3 Year: 2015 Page: 253-262
Author(s): Leonardo B. Federico, Jonathan R. de Almeida, Carlton A. Taft, Carlos H. T. de Paula da Silva

The Normal and Pathologic Roles of the Alzheimer's β -secretase, BACE1

Journal: Current Alzheimer Research
Volume: 11 Issue: 5 Year: 2014 Page: 441-449
Author(s): Patty C. Kandalepas, Robert Vassar

An Update on Natural Occurrence and Biological Activity of Chromones

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 2 Year: 2011 Page: 3825-3852
Author(s): S. K. Sharma, S. Kumar, K. Chand, A. Kathuria, A. Gupta, R. Jain

A Novel Immunotherapy for Alzheimers Disease: Antibodies against the β-Secretase Cleavage Site of APP

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 437-445
Author(s): Michal Arbel, Beka Solomon

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