Search Result "HepaRG"
Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells
Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 14-23
Author(s): Akira Ogasawara,Nozomu Kato,Nao Torimoto,Fumika Aohara,Rikiya Ohashi,Yasuhiro Yamada,Hideki Taniguchi
Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays
Journal: Drug Metabolism Letters
Volume: 9 Issue: 1 Year: 2015 Page: 3-7
Author(s): Norie Murayama,Takashi Usui,Nicky Slawny,Christophe Chesne,Hiroshi Yamazaki
In vitro Characterization of NPS Metabolites Produced by Human Liver Microsomes and the HepaRG Cell Line Using Liquid Chromatographyhigh Resolution Mass Spectrometry (LC-HRMS) Analysis: Application to Furanyl Fentanyl
Journal: Current Pharmaceutical Biotechnology
Volume: 18 Issue: 10 Year: 2017 Page: 806-814
Author(s): Camille Richeval,Thomas Gicquel,Chloe Hugbart,Brendan Le Dare,Delphine Allorge,Isabelle Morel,Jean-michel Gaulier
The Use of HepaRG and Human Hepatocyte Data in Predicting CYP Induction Drug-Drug Interactions via Static Equation and Dynamic Mechanistic Modelling Approaches
Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 870-885
Author(s): Ken Grime, Douglas D. Ferguson, Robert J. Riley
New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery
Journal: Drug Metabolism Letters
Volume: 10 Issue: 3 Year: 2016 Page: 152-160
Author(s): Akira Ogasawara,Nao Torimoto,Naoki Tsuda,Fumika Aohara,Rikiya Ohashi,Yasuhiro Yamada,Hideki Taniguchi
Cannabidiol and Indole-3-carbinol Reduce Intracellular Lipid DropletAccumulation in HepaRG, A Human Liver Cell Line, as well as in HumanAdipocytes
Journal: The Natural Products Journal
Volume: 14 Issue: 2 Year: 2024 Page: 71-80
Author(s): Megan E. Solan,Maria T. Fernandez-Luna
In vitro Toxicity Evaluation and in vivo Biodistribution of Polymeric Micelles Derived from Poly(ethylene glycol)-b-poly(benzyl malate) Copolymers
Journal: Pharmaceutical Nanotechnology
Volume: 4 Issue: 1 Year: 2016 Page: 24-37
Author(s): Elise Vene,Kathleen Jarnouen,Zhi Wei Huang,Bedhouche Wahib,Tristan Montier,Sandrine Cammas-Marion,Pascal Loyer
“Branched Tail” Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip
Journal: Drug Metabolism Letters
Volume: 13 Issue: 1 Year: 2019 Page: 45-52
Author(s): Andrey A. Poloznikov,Sergey V. Nikulin,Arpenik A. Zakhariants,Anna Y. Khristichenko,Dmitry M. Hushpulian,Ildar N. Gazizov,Vladimir I. Tishkov,Irina G. Gazaryan
Plasma Concentration Profiles for Hepatotoxic Pyrrolizidine AlkaloidSenkirkine in Humans Extrapolated from Rat Data Sets Using a SimplifiedPhysiologically Based Pharmacokinetic Model
Journal: Drug Metabolism and Bioanalysis Letters
Volume: 15 Issue: 1 Year: 2022 Page: 64-69
Author(s): Yusuke Kamiya,Tomonori Miura,Airi Kato,Norie Murayama,Makiko Shimizu,Hiroshi Yamazaki
3D Hepatic In Vitro Models as Tools for Toxicity Studies
Journal: Current Tissue Engineering
Volume: 2 Issue: 1 Year: 2013 Page: 78-89
Author(s): D. Mueller, E. Heinzle, F. Noor