Current Drug Targets - Cardiovascular & Hematological Disorders

Aims & Scope

Cardiovascular & Hematological Disorders-Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in cardiovascular and hematological disorders e.g. disease specific proteins, ...read more

  • ISSN (Print): 1568-0061
  • ISSN (Online): 1568-0061
  • Volume: 5
  • Issues: 6, 2005
Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 5, Issue 6, 2005


Editorial: Emerging Pharmacological Strategies for the Prevention of Atherosclerotic Disease Progression

Pp: 431-432

Author(s): Paul Schoenhagen and Steven E. Nissen

DOI: 10.2174/156800605774962013

Animal Models of Atherosclerosis Progression: Current Concepts

Pp: 433-440

Author(s): A. C. McMahon, L. Kritharides and H. C. Lowe

DOI: 10.2174/156800605774962031

HMG-CoA Reductase Inhibitors: Effects on Chronic Subacute Inflammation and Onset of Atherosclerosis Induced by Dietary Cholesterol

Pp: 441-453

Author(s): R. Kleemann and T. Kooistra

DOI: 10.2174/156800605774962077

Cholesterol Absorption Blockade with Ezetimibe

Pp: 455-462

Author(s): Peter P. Toth and Michael H. Davidson

DOI: 10.2174/156800605774962086

Inhibitors of Acyl-Coenzyme A: Cholesterol Acyltransferase

Pp: 463-469

Author(s): Akira Miyazaki, Tomoko Kanome and Takuya Watanabe

DOI: 10.2174/156800605774962040

Increasing High-Density Lipoprotein Cholesterol Through Cholesteryl Ester Transfer Protein Inhibition: A Next Step in the Fight Against Cardiovascular Disease?

Pp: 481-488

Author(s): W. A. Van der Steeg, K. El-Harchaoui, J. A. Kuivenhoven and J. J.P. Kastelein

DOI: 10.2174/156800605774961997

Preventing Atherosclerosis with Angiotensin-Converting Enzyme Inhibitors: Emphasis on Diabetic Atherosclerosis

Pp: 503-512

Author(s): T. J. Allen and K. A. Jandeleit-Dahm

DOI: 10.2174/156800605774962068

Peroxisome Proliferator-Activated Receptor ?? (PPAR??) and Atherosclerosis

Pp: 513-525

Author(s): I. Gouni-Berthold and W. Krone

DOI: 10.2174/156800605774962022

Lipoprotein-associated Phospholipase A2: A Potential Therapeutic Target for Atherosclerosis

Pp: 527-532

Author(s): A. Zalewski, C. Macphee and J. J. Nelson

DOI: 10.2174/156800605774962103

Liver X Receptors: Potential Novel Targets in Cardiovascular Diseases

Pp: 533-540

Author(s): Dennis Bruemmer and Ronald E. Law

DOI: 10.2174/156800605774961988

Matrix Metalloproteinases: A Potential Therapeutic Target in Atherosclerosis

Pp: 541-548

Author(s): Mustapha Rouis

DOI: 10.2174/156800605774961979

Non-invasive Atherosclerosis Imaging: Use to Assess Response to Novel or Combination Lipid Therapies

Pp: 557-564

Author(s): Todd C. Villines and Allen J. Taylor

DOI: 10.2174/156800605774962059

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    • Booting (91.97ms)time
    • Application (178ms)time
    • 1 x Application (65.94%)
      178ms
      1 x Booting (34.06%)
      91.97ms
      9 templates were rendered
      • journal_menujournal_menu.blade.php#?blade
      • includes.journal_bannerjournal_banner.blade.php#?blade
      • includes.issue_articleissue_article.blade.php#?blade
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      • includes.journal_right_bannerjournal_right_banner.blade.php#?blade
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      • layouts._login_access_login_access.blade.php#?blade
      • layouts._main_menu_main_menu.blade.php#?blade
      • layouts._footer_menu_footer_menu.blade.php#?blade
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        • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
        • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
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        990μsbetabenthamscien_newUserAccessCheck.php#24
        Backtrace
        • 11. middleware::check_user_access:24
        • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
        • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
      • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('51269529','/issue/1029/1',1,1745558818,1745558818)
        150μsbetabenthamscien_newUserAccessCheck.php#27
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        • 11. middleware::check_user_access:27
        • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
        • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
      • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 51269529 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 51269529) limit 1
        12.83msbetabenthamscien_newUserAccess.php#784
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        • 1: 51269529
        • 2: 51269529
        • 3: 51269529
        • 4: 51269529
        • 5: 51269529
        • 6: 51269529
        • 7: 51269529
        • 8: 51269529
        • 9: 51269529
        • 10: 51269529
        • 11: 51269529
        • 12: 51269529
        • 13: 51269529
        • 14: 51269529
        • 15: 51269529
        Backtrace
        • 14. app/Models/UserAccess/UserAccess.php:784
        • 15. middleware::check_user_access:63
        • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
        • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • select * from `issue` where `issue_id` = '1029' order by cast(issue.title as signed) desc
        330μsbetabenthamscien_newIssue.php#157
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        • 0: 1029
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        • 13. app/Models/Issue.php:157
        • 14. app/Http/Controllers/IssueController.php:861
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select * from `journal` where `journal_id` = 83 limit 1
        1.02msbetabenthamscien_newJournal.php#64
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        • 14. app/Models/Journal.php:64
        • 15. app/Http/Controllers/IssueController.php:863
        • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select * from `volume` where `volume_id` = 664
        270μsbetabenthamscien_newVolume.php#88
        Bindings
        • 0: 664
        Backtrace
        • 13. app/Models/Volume.php:88
        • 14. app/Http/Controllers/IssueController.php:865
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select v.*, j.title, j.subtitle, y.year from volume v inner join journal j on v.journal_id = j.journal_id inner join year y on v.year_id = y.id where 1 and v.volume_id = 664
        340μsbetabenthamscien_newVolume.php#292
        Backtrace
        • 11. app/Models/Volume.php:292
        • 12. app/Http/Controllers/IssueController.php:867
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 1 and a.journal_id = 83 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`last_modified` desc
        4.49msbetabenthamscien_newArticle.php#527
        Backtrace
        • 13. app/Models/Article.php:527
        • 14. app/Http/Controllers/IssueController.php:868
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select a.nid,a.publish_on, a.pmid,a.article_id,a.doi,j.journal_id,j.subtitle,v.volume_name,a.volume_id as volume_id, a.issue_id,a.title,first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"),asec.title as article_section,at.type_name as article_type_name, a.article_id as ArticleID ,is_epub,epub_price,epub_type,a.created, y.year from `article` as `a` left join `article_section` as `asec` on `asec`.`art_sec_id` = `a`.`is_epub` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal` as `j` on `j`.`journal_id` = `a`.`journal_id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_epub = 4 and a.journal_id = 83 and a.is_uploaded = 1 group by `a`.`article_id` order by `a`.`last_modified` desc
        1.27msbetabenthamscien_newArticle.php#527
        Backtrace
        • 13. app/Models/Article.php:527
        • 14. app/Http/Controllers/IssueController.php:869
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select substring_index(GROUP_CONCAT(i.nicename ORDER BY i.priority SEPARATOR ', '), ',', 3) as indexing_title, COUNT(i.nicename) as indexing_occurrences from `indexing_journal` as `ij` inner join `indexing_agencies` as `i` on `ij`.`index_id` = `i`.`index_id` where `ij`.`journal_id` = 83 and `i`.`status` = 1 and `i`.`index_flag` = 1 group by `ij`.`journal_id` limit 1
        330μsbetabenthamscien_newIndexing.php#415
        Bindings
        • 0: 83
        • 1: 1
        • 2: 1
        Backtrace
        • 14. app/Models/Indexing.php:415
        • 15. app/Http/Controllers/IssueController.php:870
        • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select * from `journal` where `journal_id` = 83 limit 1
        1.02msbetabenthamscien_newArticle.php#426
        Bindings
        • 0: 83
        Backtrace
        • 14. app/Models/Article.php:426
        • 15. app/Http/Controllers/IssueController.php:872
        • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select count(*) as aggregate from (select a.publish_on,a.article_id,a.elocator, a.nid,a.pmid, a.title,a.altmetric_score,a.altmetric_url,a.kudos_url, j.content_type_access_id, first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"), a.graph_abs_lg_filename,a.is_epub, a.is_epub as epub, a.graph_abs_sm_filename,a.journal_id,a.volume_id,a.issue_id, a.doi,m.month,y.year, at.type_name article_type_name,a.html_filename,a.prc_filename,a.epub_filename,v.volume_name,i.title as issue, i.type as issue_type, js.js_title, js.js_id, (select GROUP_CONCAT(CONCAT(COALESCE(first_name, ""),"", last_name)) from author aa where aa.article_id = a.article_id) as authors from `article` as `a` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal_section` as `js` on `js`.`js_id` = `a`.`js_id` left join `journal_access` as `j` on `a`.`article_id` = `j`.`content_type_id` and `j`.`content_type` = 'a' left join `issue` as `i` on `a`.`issue_id` = `i`.`issue_id` left join `month` as `m` on `i`.`month_id` = `m`.`id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_uploaded = 1 and a.issue_id = 1029 group by `a`.`article_id`) as `aggregate_table`
        2.08msbetabenthamscien_newArticle.php#468
        Backtrace
        • 16. app/Models/Article.php:468
        • 17. app/Http/Controllers/IssueController.php:872
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select a.publish_on,a.article_id,a.elocator, a.nid,a.pmid, a.title,a.altmetric_score,a.altmetric_url,a.kudos_url, j.content_type_access_id, first_page, last_page, page_count,abstract,ifnull(is_abstract,"y"), a.graph_abs_lg_filename,a.is_epub, a.is_epub as epub, a.graph_abs_sm_filename,a.journal_id,a.volume_id,a.issue_id, a.doi,m.month,y.year, at.type_name article_type_name,a.html_filename,a.prc_filename,a.epub_filename,v.volume_name,i.title as issue, i.type as issue_type, js.js_title, js.js_id, (select GROUP_CONCAT(CONCAT(COALESCE(first_name, ""),"", last_name)) from author aa where aa.article_id = a.article_id) as authors from `article` as `a` left join `article_type` as `at` on `at`.`art_type_id` = `a`.`art_type` left join `journal_section` as `js` on `js`.`js_id` = `a`.`js_id` left join `journal_access` as `j` on `a`.`article_id` = `j`.`content_type_id` and `j`.`content_type` = 'a' left join `issue` as `i` on `a`.`issue_id` = `i`.`issue_id` left join `month` as `m` on `i`.`month_id` = `m`.`id` inner join `volume` as `v` on `a`.`volume_id` = `v`.`volume_id` inner join `year` as `y` on `v`.`year_id` = `y`.`id` where a.article_status != "W" and a.is_uploaded = 1 and a.issue_id = 1029 group by `a`.`article_id` order by cast(a.article_no as SIGNED) asc, a.publish_on asc limit 20 offset 0
        1.28msbetabenthamscien_newArticle.php#468
        Backtrace
        • 14. app/Models/Article.php:468
        • 15. app/Http/Controllers/IssueController.php:872
        • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '664' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
        430μsbetabenthamscien_newContentAccess.php#647
        Backtrace
        • 11. app/Models/ContentAccess.php:647
        • 12. app/Http/Controllers/IssueController.php:900
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select count(*) as total_count, content_type_access_id as access_type from journal_access where content_type_id = '1029' and content_type = 'i' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
        330μsbetabenthamscien_newContentAccess.php#647
        Backtrace
        • 11. app/Models/ContentAccess.php:647
        • 12. app/Http/Controllers/IssueController.php:907
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 664) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 664) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"volume" as access_level,"" as issue_id,"" as article_id from `user_access_journal_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 664)
        830μsbetabenthamscien_newUserAccess.php#1266
        Backtrace
        • 13. app/Models/UserAccess/UserAccess.php:1266
        • 14. app/Http/Controllers/IssueController.php:919
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"issue" as access_level,j.issue_id,"" as article_id from `user_access_issue_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029)
        830μsbetabenthamscien_newUserAccess.php#1266
        Backtrace
        • 13. app/Models/UserAccess/UserAccess.php:1266
        • 14. app/Http/Controllers/IssueController.php:932
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select * from `journal_access` where `content_type_id` in (35712, 35713, 35714, 35715, 35716, 35717, 35718, 35719, 35720, 35721, 35722, 35723, 35724, 35725, 35726) and `content_type` = 'a' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
        990μsbetabenthamscien_newContentAccess.php#616
        Bindings
        • 0: 35712
        • 1: 35713
        • 2: 35714
        • 3: 35715
        • 4: 35716
        • 5: 35717
        • 6: 35718
        • 7: 35719
        • 8: 35720
        • 9: 35721
        • 10: 35722
        • 11: 35723
        • 12: 35724
        • 13: 35725
        • 14: 35726
        • 15: a
        Backtrace
        • 13. app/Models/ContentAccess.php:616
        • 14. app/Http/Controllers/IssueController.php:945
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"article" as access_level, j.issue_id, j.article_id from `user_access_article_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51269529 and j.to_ip >=51269529 )) and ((j.from_date <= 1745558818 and j.to_date >= 1745558818 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.issue_id = 1029)
        880μsbetabenthamscien_newUserAccess.php#1266
        Backtrace
        • 13. app/Models/UserAccess/UserAccess.php:1266
        • 14. app/Http/Controllers/IssueController.php:1022
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35712' order by au.sequence
        390μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35713' order by au.sequence
        320μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35714' order by au.sequence
        310μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35715' order by au.sequence
        300μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35716' order by au.sequence
        310μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35717' order by au.sequence
        330μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35718' order by au.sequence
        310μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35719' order by au.sequence
        300μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35720' order by au.sequence
        310μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35721' order by au.sequence
        330μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35722' order by au.sequence
        340μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35723' order by au.sequence
        320μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35724' order by au.sequence
        300μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35725' order by au.sequence
        300μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select CONCAT(ifnull(au.first_name,''),' ',IFNULL(CONCAT(au.initials,' '),''), au.last_name) as authors, au.* FROM author au where article_id = '35726' order by au.sequence
        310μsbetabenthamscien_newAuthor.php#137
        Backtrace
        • 11. app/Models/Author.php:137
        • 12. app/Http/Controllers/IssueController.php:1154
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select * from `node_meta` where `nid` = 660 limit 1
        310μsbetabenthamscien_newMeta.php#59
        Bindings
        • 0: 660
        Backtrace
        • 14. app/Models/Meta.php:59
        • 15. app/Http/Controllers/IssueController.php:1181
        • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 83 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
        37msbetabenthamscien_newIssue.php#295
        Backtrace
        • 11. app/Models/Issue.php:295
        • 12. app/Http/Controllers/IssueController.php:1188
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues from journal j join volume v on j.journal_id = v.journal_id join year y on v.year_id = y.id where j.journal_id = 83 and y.year = 2025 order by v.volume_name+0 desc limit 1
        510μsbetabenthamscien_newIssue.php#295
        Backtrace
        • 11. app/Models/Issue.php:295
        • 12. app/Http/Controllers/IssueController.php:1189
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • Select j.subtitle, v.volume_id as volume_id,v.year_id,y.year as year,v.volume_name, v.total_no_of_issues, i.issue_id as issue_id,i.title as issue, i.publication_date as issue_pub_date from journal j join volume v on j.journal_id = v.journal_id join issue i on v.volume_id = i.volume_id join article a on a.issue_id = i.issue_id join year y on v.year_id = y.id where j.journal_id = 83 and i.is_uploaded = 1 order by v.volume_name+0 desc, i.title+0 desc limit 1
        35.95msbetabenthamscien_newIssue.php#295
        Backtrace
        • 11. app/Models/Issue.php:295
        • 12. app/Http/Controllers/IssueController.php:1191
        • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select `subtitle` from `journal` where `continues_publication_journal` = 1
        770μsbetabenthamscien_newArticle.php#1959
        Bindings
        • 0: 1
        Backtrace
        • 13. app/Models/Article.php:1959
        • 14. app/Http/Controllers/IssueController.php:1197
        • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` inner join `journal` as `j` on `j`.`journal_id` = `bd`.`content_id` where `b`.`banner_journal` = 1 and `bd`.`content_type` = 'J' and `bd`.`content_id` = 83 and `b`.`banner_from_date` <= 1745558818 and `b`.`banner_to_date` >= 1745558818 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
        1.29msbetabenthamscien_newBanner.php#189
        Bindings
        • 0: 1
        • 1: J
        • 2: 83
        • 3: 1745558818
        • 4: 1745558818
        • 5: A
        Backtrace
        • 13. app/Models/Banner.php:189
        • 14. app/Http/helpers.php:404
        • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
      • select count(*) as aggregate from `uc_cart_products` where cart_id='c947c0e75f3a7c9dac159534a398d7f1'
        210μsbetabenthamscien_newCart.php#271
        Backtrace
        • 15. app/Models/Cart.php:271
        • 16. view::layouts._main_menu:13
        • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
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          ClearShow all
          Date ↕MethodURLData
          #12025-04-25 05:26:58GET/issue/1029/1941