Current Cancer Drug Targets

Current Cancer Drug Targets aims to cover all the latest and outstanding developments in full spectrum of cancer drug discovery and development, including but not limited to cellular and molecular biology, genomics, proteomics, metabolomics, medicinal chemistry, pharmacology, toxicology, and biochemistry ...read more

  • ISSN (Print): 1568-0096
  • ISSN (Online): 1873-5576
  • Volume: 25
  • Issues: 12, 2025
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Current Cancer Drug Targets
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Open Access Articles

Research Article
Liquid-Liquid Phase Separation in the Prognosis of Lung Adenocarcinoma: An Integrated Analysis

Pp: 323-334

Volume: 25, Issue: 4

Authors: Qilong Wang, Nannan Sun, Jianhao Li, Fengxiang Huang and Zhao Zhang*

DOI: 10.2174/0115680096345676241001081051

Published on: November 6, 2024

Research Article
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway

Pp: 294-305

Volume: 25, Issue: 3

Authors: Yiping Zheng, Jianfeng Cai, Qiuhong Ji, Luanmei Liu, Kaijun Liao, Lie Dong, Jie Gao and Yinghui Huang*

DOI: 10.2174/0115680096337237240909101904

Published on: October 1, 2024

Research Article
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT

Pp: 72-82

Volume: 25, Issue: 1

Authors: Xin Chen, Zhenbang Zhou, Pengting Tang, Feiya Du, Shuqian Wang, Jia Yao, Shufen Zhang, Jiajing Huang, Xuemei Lu, Wei Chen, Xiaofang Yu*, Yu Liu* and Hao Liu*

DOI: 10.2174/0115680096281231240202073558

Published on: February 26, 2024

Research Article
Macranthoside B Suppresses the Growth of Adenocarcinoma of Esophagogastric Junction by Regulating Iron Homeostasis and Ferroptosis through NRF2 Inhibition

Authors: Lingling Wang, Guangzhao Pan, Sichao Tian, Che Zhang, Fangfang Tao and Jiang-Jiang Qin*

DOI: 10.2174/0115680096370291250109103853

Published on: January 22, 2025

Research Article
Efficacy and Safety of PD-1/L1 Inhibitors Combined with Anlotinib versus PD-1 /L1 Inhibitors Combined with Bevacizumab in Second-Line Treatment of Advanced Non-Small Cell Lung Cancer Patients: A Comparative Cohort Study

Authors: Xiaobing Li*, De Wu, Yi Peng, Jing Tang and Yuebing Wu

DOI: 10.2174/0115680096338045241117161228

Published on: January 16, 2025

Research Article
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)

Authors: Feiting Xie, Qiugang Zhu, Shizhou Yang, Xiaofen Jin, Danqi Ruan, Lingfang Wang, Yang Li, Fang Ren and Xiaojing Chen*

DOI: 10.2174/0115680096332050241022102545

Published on: January 24, 2025

Research Article
Tectorigenin Inhibits Glycolysis-induced Cell Growth and Proliferation by Modulating LncRNA CCAT2/miR-145 Pathway in Colorectal Cancer

Pp: 1071-1079

Volume: 24, Issue: 10

Authors: Ying Xing, Bofan Lin, Baoxinzi Liu, Jie Shao and Zhichao Jin*

DOI: 10.2174/0115680096274757231219072003

Published on: January 11, 2024

Research Article
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma

Pp: 804-819

Volume: 24, Issue: 8

Authors: Juntao Huang*, Ziqian Xu, Zhenzhen Wang, Chongchang Zhou and Yi Shen*

DOI: 10.2174/0115680096274798231121053634

Published on: January 4, 2024

Research Article
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer

Pp: 733-748

Volume: 24, Issue: 7

Authors: Yanglong Guo, Xi Chen, Xuedong Tang, Shan Pan, Tao Zhu and Yingli Zhang*

DOI: 10.2174/0115680096271476231226174810

Published on: January 1, 2024

Research Article
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells

Pp: 720-732

Volume: 24, Issue: 7

Authors: Kelly C. Arias Cardenas, Clinton W. Enos, Mark R. Spear*, Dana E. Austin, Raghad Almofeez, Stephanie Kortchak, Lauren Pincus, Hua-bei Guo, Samuel Dolezal, J. Michael Pierce, Emma Furth, Cyrille Gineste, Yongjun Kwon and Cohava Gelber

DOI: 10.2174/0115680096260614231115192343

Published on: January 4, 2024

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