Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. Volume 9 features reviews on these topics: - Dietary Strategy for Cancer Therapy - Amino Acid Restrictions and Beyond - The Revolutionary Potential of Noble Metal Nanoparticles as Anti-Cancer Agents: State-of-the-Art Applications and Future Perspectives - Algal Polysaccharides as Promising Anticancer Agents - Cardiotoxicity Caused by Doxorubicin and Trastuzumab: Current Understanding for Future Preventive Strategies - Emodin: Anticancer Agent

Handbook of Laparoscopy Instruments covers the essential components of laparoscopic instruments and technology. It presents accessible information covering key topics on the subject: Ø Basic and specialized laparoscopic instruments Ø Image production Ø Pneumoperitoneum maintenance Ø Ergonomics Ø Sterilization procedures Ø Optical devices Ø Operation theatre layout and setup Ø Operative hand instruments Ø Robotic Surgery This book is an indispensable resource recommended for students and surgical residents who need an understanding of instruments and procedures in laparoscopic surgery. It is also intended to help medical professionals who want to start laparoscopy units in their clinics.

This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty. Key Features: Practical, patient-centered guide emphasizing a clinical approach. Demonstrative clinical cases for enhanced understanding. Evaluation of perfusional indices using noninvasive and noncontact imaging techniques. High histopathological correlation of structural tissue characterization with microvascular evaluation. Exploration of new perfusion concepts and their role in disease pathogenesis. Part 2 covers advanced topics in OCT-A for choroidal and vitreoretinal disorders. Chapters explore macular perfusional repercussions in obstructive venous vascular phenomena, OCT-A findings in retinal infarction, and the role of macular perfusion in myopic macular traction maculopathy. Further discussions include postoperative perfusional findings in vitreoretinopathy, distinctions in choroidal vasculopathies, and the application of OCT-A in managing pathological choroidal neovascularization. The part concludes with a review of postoperative membrane formation, the usefulness of OCT-A in neurodegenerative diseases, and the evaluation of arterial occlusions and choroidal neovascularization management.

Female Arousal and Orgasm: Anatomy, Physiology, Behaviour and Evolution is the first comprehensive and accessible work on all aspects of human female sexual desire, arousal and orgasm. The book attempts to answer basic questions about the female orgasm and questions contradictory information on the topic. The book starts with a summary of important early research on human sex before providing detailed descriptions of female sexual anatomy, histology and neuromuscular biology. It concludes with a discussion of the high heritability of female orgasmicity and evidence for and against female orgasm providing an evolutionary advantage. The author has attempted to gather as much information on the subject as possible, including medical images, anonymized survey data and previously unreported trends. The groundbreaking book gives a scientific perspective on sexual arousal in women, and helps to uncover information gaps about this fascinating yet complex phenomenon.

This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty. Key Features: Practical, patient-centered guide emphasizing a clinical approach. Demonstrative clinical cases for enhanced understanding. Evaluation of perfusional indices using noninvasive and noncontact imaging techniques. High histopathological correlation of structural tissue characterization with microvascular evaluation. Exploration of new perfusion concepts and their role in disease pathogenesis. Part 1 of the book focuses on OCT-A principles and applications in ophthalmology. It covers the basics of OCT-A, its contributions to eye disease study and treatment, and a comparative analysis with OCT for choroidal and vitreoretinal diseases. Additional information on nomenclature, normative datasets, and data analysis, presenting indices in different eye conditions is also presented. The emphasis is on macular perfusion in surgically resolved myopic foveoretinal detachment, postoperative evaluation in retinal detachment, and long-term analysis in diabetic retinopathy.

This comprehensive reference is a timely exploration of two vital aspects of triple-negative breast cancer. The book offers a holistic perspective that helps readers to navigate the challenges of managing triple-negative breast cancer (TNBC) with knowledge and confidence. Understanding Ethnic Disparities and Targeted Therapies: This section provides a critical overview of the ethnic disparities and the latest targeted therapies available for patients facing advanced or metastatic triple-negative breast cancer (TNBC). Empowering Patients and Enhancing Communication: This section dives into the essential role of patient education, empowerment, effective communication with medical teams, and psychological or supportive approaches, providing invaluable insights into managing advanced or metastatic breast cancer (BC). Key Features: Introduces a groundbreaking perspective on the TNBC journey, encouraging patients to view their battle with the disease as an opportunity to leverage modern pharmacological advancements and psychological support for improved outcomes. Bridges the gap between clinical or research-related aspects of BC management and the personal needs and expectations of patients, promoting a more holistic approach. Invites perspectives from a wide range of medical professionals, from oncologists and cardiologists to psychologists and nurses, to engage in open dialogues with patients, offering practical education and crucial support. Provides a wealth of helpful resources (including an appendix) for both patients and their medical caregivers, fostering a comprehensive and supportive approach to managing TNBC. This book is an informative resource for medical professionals, researchers, and patients, who want to understand the complexities of triple-negative breast cancer and apply current knowledge in their clinical and caregiving practice.

Nanotechnology has shown immense promise for advancing blood glucose control. This technology offers the potential to safeguard pancreatic cells from autoimmune destruction by driving the creation of innovative therapeutic agents that can be delivered to specific targets. In this book, you will find a comprehensive exploration of diabetes and its approved medical treatments. The book delves into how nanotechnology can amplify the efficacy of current treatment modalities, potentially paving the way for a gene therapy solution to combat this disease. Starting with the history of diabetes treatment, the book explains treatment challenges for diabetes before getting into the three ways nanoscience is helping in diabetes treatment: insulin delivery, drug delivery and nucleotide delivery. Each chapter is contributed by accomplished experts in their respective fields, who strive to offer a thorough, yet accessible discussion of the subject.

Learn the skills of medical history taking and physical examination with this accessible and comprehensive textbook. Designed for medical students and clinicians, it simplifies complex concepts and procedures to empower you with essential skills for effective patient consultation. Key Features -Clear and Simple Language: This book uses plain and straightforward language, making the intricate world of medical history taking and physical examination easy to understand, even for beginners. -Real Illustrations: Learn from real pictures that vividly depict clinical scenarios, helping you bridge the gap between theory and practice. -Step-by-Step Guidelines: Follow systematic guidelines for history taking and physical examination. From patient introduction and consent to comprehensive body system examinations, each step is clearly outlined, ensuring you never miss a crucial detail. -Specialized Examination Section: Includes a specialized examination section, covering various body systems like cardiovascular, respiratory, abdominal, and the central nervous system. Understand the physical basis of clinical signs to enhance your diagnostic skills. Quick Guide in History Taking and Physical Examination helps you to master the art of clinical examination, develop the confidence to take accurate medical histories, and interpret symptoms and signs effectively. It serves as an essential companion for medical students and residents on their journey to become a proficient clinician.

In the battle against the COVID-19 pandemic, the integration of Internet of Things (IoT) technologies has played a pivotal role in reshaping public health and healthcare delivery. Interconnected devices have demonstrated their capacity to collect, transmit, and analyze data, significantly impacting various aspects of pandemic management. COVID-19 Monitoring with IoT Devices is a comprehensive guide to measuring the impact of COVID-19 infection and monitoring outbreak metrics. Beginning with an introduction to SARS-CoV-2 and its symptoms, the book presents chapters on machine learning (supervised and unsupervised algorithms) and techniques to predict COVID-19 outcomes. The book concludes with the role of IoT technology in detecting COVID-19 infections within a community, showcasing different computing models applicable to specific use-cases. Key Features: Explores the pivotal role of IoT technology in the fight against the COVID-19 pandemic. Covers a data-driven approach to COVID-19 monitoring by explaining methods for data collection, prediction, and analysis. Includes specific recommendations for machine learning algorithms designed for COVID-19 monitoring. Easy-to-read structured chapters suitable for novices in computer science and biomedical engineering. COVID-19 Monitoring with IoT Devices provides a valuable resource for understanding the role of IoT technology in managing and mitigating the impact of COVID-19, and developing adequate infection control policies. It also showcases the potential of IoT for future research and applications in the healthcare sector. This book is intended for a diverse readership, including academicians, industry professionals, researchers, and healthcare practitioners.

Frontiers in Clinical Drug Research – Anti Infectives (Volume 9) is a book series that provides updated reviews on the latest advancements in development of pharmaceutical agents for treating infectious diseases. The series covers various topics, including chemistry, pharmacology, molecular biology, and biochemistry of natural and synthetic drugs. Additionally, it addresses multi-drug resistance and pre-clinical/clinical findings on antibiotics, vaccines, antifungal agents, and antitubercular drugs. This series is an invaluable resource for pharmaceutical scientists and postgraduate students, offering critical information to support clinical trials and research in anti-infective drug discovery and epidemiology. The ninth volume presents five in-depth reviews, with topics including mature drugs and antivirals for COVID-19, bacteriocins as potent anti-infective agents, therapeutic interventions targeting free radicals in viral diseases, and a detailed exploration of natural anti-infective agents. The five reviews included in this volume are: - The role of mature drugs in the COVID-19 era - Antivirals to treat COVID-19 - Ribosomally synthesized bacteriocins as potent anti-infective agents - Therapeutic interventions against free radicals in viral diseases - A comprehensive overview of natural anti-infective agents