Medicinal Chemistry, a peer-reviewed journal, aims to cover all the latest outstanding developments in medicinal chemistry and rational drug design. The journal publishes original research, full-length/mini-review articles, short communications, letters, and guest-edited thematic issues covering recent research and developments in ...read more
eISBN: 978-981-5256-56-7
ISBN: 978-981-5256-57-4
This book provides an in-depth and comprehensive overview of andrographolides and their analogues, highlighting their botanical origins, phytochemistry, pharmacological properties, and biotechnological applications. It explores the isolation, purification, and spectroscopic characterization of andrographolides from natural sources, emphasizing their therapeutic potential in antidiabetic studies and other medicinal uses. The book also explains cultivation techniques, agronomic strategies for Andrographis species, genetic improvements, and in vivo extraction methods aimed at enhancing andrographolide yields, with a focus on commercial cultivation and export strategies. Dedicated chapters, contributed by experts, discuss the ethnobotanical significance of Andrographis species, traditional medicinal formulations, and advanced biotechnological interventions for conservation and utilization. Recent breakthroughs in understanding andrographolides'biosynthesis, metabolism, safety aspects, and promising applications in treating diabetes, cancer, inflammation, liver diseases, and neurological disorders are also covered. Readers will gain insight into how andrographolide analogues can be developed as "lead molecules" for creating next-generation phytodrugs. Key Features - Provides a comprehensive account of andrographolide-producing plant sources and their phytochemical and pharmacological properties. - Explores the role of biotechnology in enhancing andrographolide production through in vivo and in vitro methods. - Highlights the therapeutic efficacy of andrographolides and analogues in antidiabetic, anticancer, hepatoprotective, and anti-inflammatory drug development. - Discusses cutting-edge advancements in the biosynthesis and semisynthetic derivatives of andrographolides. - Covers cultivation, agronomic techniques, and genetic improvements to optimize andrographolide production for commercial applications. This book is a valuable resource for researchers, pharmacologists, biotechnologists, and biomedical professionals focused on natural product-based drug discovery involving andrographolide.
eISBN: 978-981-5274-10-3
ISBN: 978-981-5274-11-0
Metabolites of Medicinal Plants: Insightful Approaches provides a comprehensive exploration of the bioactive compounds found in medicinal plants and their pharmacological significance. The book covers key topics such as the economics of medicinal and anticancer plants, phytochemistry, therapeutic potential, and advanced applications like nanotechnology-based drug delivery systems and CRISPR-Cas techniques. It also examines the role of these plants in combating diseases like diabetes and metabolic syndrome and their role in traditional medicine systems. This resource is essential for students, researchers, and professionals in phytochemistry, pharmacology, drug discovery, and healthcare practices. Key Features: 1. Wide range of topics from medicinal plant economics to pharmacological applications. 2. Latest discoveries in plant bioactive compounds and their therapeutic uses. 3. Novel drug delivery methods to enhance efficacy. 4. Linking genes to metabolites through advanced omics approaches.
eISBN: 978-981-5274-88-2
ISBN: 978-981-5274-89-9
Herbs for Disease Prevention and Treatment offers a comprehensive exploration of the therapeutic potential of herbs and their bioactive compounds in preventing and managing various diseases. This book delves into the use of marine macroalgae in diabetes management, the role of herbal supplements and nutraceuticals in disease prevention, and the application of herbs as dietary medicine. It also covers traditional medicinal plants, the historical and contemporary use of herbal medicine, and innovative techniques like GC-MS and LC-MS-MS for identifying phytochemicals effective against COVID-19. Additionally, it includes a review of the impact of repeated heating on plant edible oils and explores plant-based treatments for kidney diseases. Aimed at healthcare professionals, researchers, and students in the fields of herbal medicine, pharmacology, and nutrition, this book serves as an essential resource for understanding the role of herbs in modern healthcare.
eISBN: 978-981-5223-88-0
ISBN: 978-981-5223-89-7
Anthocyanins are a diverse group of phytochemicals used for the treatment and management of acute and chronic ailments. This book is a comprehensive guide to anthocyanins and their importance as pharmaceutical and nutraceutical agents. The book provides detailed information about anthocyanin sources and their application in the treatment of diseases including cancer, gastric disorders, infertility, metabolic diseases, and neurological disorders. Key features · Explains the importance of phytochemicals and nutraceuticals · Provides details of anthocyanin sources and mechanisms of action · Includes chapters dedicated to the use of anthocyanins to treat specific diseases · Provides a summary of the market for anthocyanins as a pharmaceutical and nutraceutical product · Includes scientific references
eISBN: 978-981-5238-12-9
ISBN: 978-981-5238-13-6
Therapeutic Insights into Herbal Medicine through the Use of Phytomolecules offers a comprehensive exploration of the pharmacological potential of plant-derived compounds. The book provides an in-depth look at the therapeutic applications of phytomolecules in various health conditions. It begins with an analysis of bioactive phloroglucinol compounds and progresses to cover plant-based approaches for managing rheumatoid arthritis, diabetes, cancer, neurological disorders, and antiviral activity. The volume also covers the molecular mechanisms of flavonoids, the preclinical pharmacology of Indian medicinal herbs, and the neuroprotective role of andrographolide in Parkinson's disease. Designed to inform and inspire, this book is ideal for researchers, clinicians, and students interested in the therapeutic potential of natural products.
eISBN: 978-981-5256-74-1
ISBN: 978-981-5256-75-8
The Roles and Responsibilities of Clinical Pharmacists in Hospital Settings is a comprehensive textbook designed to equip graduate pharmacy students and residents with the essential skills and knowledge needed for effective clinical pharmacy practice in hospitals. This book emphasizes the multidisciplinary nature of clinical pharmacy and the importance of adhering to international guidelines and standards. The book provides an overview of hospital pharmacy practice with an introduction to the essential requirements of a hospital environment, followed by a detailed exploration of clinical pharmacist roles across major medical subspecialties, including internal medicine, infectious diseases, intensive care, pediatrics, cardiology, and oncology. Key Features General and specialized Roles: Comprehensively covers different aspects of clinical pharmacology from basics to medical subspecialties Practical Insights: Offers practical tools, reference resources, and strategies for clinical pharmacy practice across different hospital departments. Advanced Practice: Guides readers from foundational knowledge to advanced clinical pharmacy practices, preparing them for specialized roles within hospital settings. Global Standards: Highlights the importance of multidisciplinary education and adherence to global clinical pharmacy standards. This textbook is an essential resource for pharmacy students, specialist assistants, and anyone pursuing a career in clinical pharmacy.
eISBN: 978-981-5238-54-9
ISBN: 978-981-5238-55-6
This book aims to fill research gaps in the search for chemotherapeutic and chemopreventive natural compounds. It includes a collection of detailed reviews focusing on bioactive compounds from plant sources that can be beneficial for cancer therapy. Topics covered include the role of antioxidants in cancer therapy, medicinal plants for cancer chemotherapeutics, bioactive compounds from marine plants, and a review of inhibiting nitric oxide reactions for preventing cancer. Chapters are contributed by researchers who have provided detailed lists and descriptions of the relevant plant sources, the compounds and the biochemical reactions. The book includes references for advanced reading. This book is intended as a reference for scholars and healthcare professionals studying natural medicines for cancer prevention and treatment.
eISBN: 978-981-5274-37-0
ISBN: 978-981-5274-38-7
Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate and analyze bioactive compounds from herbs and spices to develop medicines for different diseases. Science of Spices and Culinary Herbs presents current reviews on studies performed on herbs and spices. This book series is an informative resource for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are a common part of regional diets and folk medicine. The sixth volume of this series features reviews on medicinal aspects of a selection of herbs and spices, including: Pimpinella anisum L. (Anise, Aniseed) Sinapis alba L. (Mustard Seeds) Cinnamomum verum (Cinnamon) Tamarindus indica L (Tamarind) Curcuma longa (Curcumin) Glycyrrhiza glabra (Licorice).
eISBN: 978-981-5196-80-1
ISBN: 978-981-5196-81-8
The Chemistry inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. Experts in phytochemistry have contributed reviews with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Volume 3 covers several topics: the treatment of Polycystic Ovary Syndrome (PCOS), managing rheumatoid arthritis and related inflammatory conditions, orchid-derived natural flavoring and therapeutic agent Vanillin, Silymarin's utility in treating hepatic diseases, phytochemistry and pharmacological activities of Hygrophila spinosa, pharmacological and chemical aspects of Tulsi, Combretum caffrum as a potential anticancer molecule, and the roles of herbs in treating diabetes. This book is an ideal resource for scholars (in life sciences, phytomedicine and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical R&D and clinical research.
eISBN: 978-981-5196-83-2
ISBN: 978-981-5196-84-9
The Chemistry inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. Experts in phytochemistry have contributed chapters with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. These in-depth reviews cover the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Volume 4 covers these topics: the potential use of Indian spices in managing viral infections, the chemical, functional, and nutritional properties of Coriander, traditional uses, chemical components, and pharmacological properties of Sphaeranthus indicus, Copaiba oleoresins phytochemisty and the pharmacological properties of oils from Copaifera species. Additionally, the pharmacognostic profile of Nardostachys jatamansi is discussed, along with insights into the medicinal herb Bush Onion (Afrostyrax lepidophyllus) and its nutritional and medicinal values. Various aspects of plant essential oils, including their chemistry, extraction methods, and medicinal properties, and plant proteases are also covered in detail. This book is an ideal resource for scholars (in life sciences, phytomedicine and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical R & D and clinical research.