Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource.

This book is a comprehensive review of secondary metabolite production from plant tissue culture. The editors have compiled 12 meticulously organized chapters that provide the relevant theoretical and practical frameworks in this subject using empirical research findings. The goal of the book is to explain the rationale behind in vitro production of secondary metabolites from some important medicinal plants. Biotechnological strategies like metabolic engineering and the biosynthesis, transport and modulation of important secondary metabolites are explained along with research studies on specific plants. In addition to the benefits of secondary metabolites, the book also aims to highlight the commercial value of medicinal plants for pharmaceutical and healthcare ventures. Topics covered in this part include: 1. Elicitation Strategies and Metabolic Engineering to boost metabolite production with case studies in metabolic engineering with examples of Scaevola Taccada and Catharanthus Roseus. 2. Stress response investigation and the role of glandular trichomes as bio-cell factories 3. Plant growth regulators and rapid regeneration techniques using swift plantlets regeneration and phytochemical characterization 4. Nutraceuticals, antimicrobials, and genomic applications of in vitro cultures with an example of Hassawi rice and its genomics 5. Sustainable approaches for saving endangered medicinal plants The book caters to a wide readership. It primarily prepares graduate students, researchers, biotechnologists, giving them a grasp of the key methodologies in the secondary metabolite production. It is a secondary reference for support executives, industry professionals, and policymakers at corporate and government levels to understand the importance of plant tissue culture and maximizing its impact in the herbal industry.

Molecular and Physiological Insights into Plant Stress Tolerance and Applications in Agriculture Part 2 is an edited volume that presents research on plant stress responses at both molecular and physiological levels. This volume builds on the previous volume to provide additional knowledge in studies on the subject. Key Features - Explains aspects of plant genetics central to research such as the role of cytosine methylation and demethylation in plant stress responses, and the importance of epigenetic genetics in regulating plant stress responses. - Explores how Late Embryogenesis Abundant proteins affect plant cellular stress tolerance with an emphasis on their molecular mechanisms and potential implications. - Focuses on beneficial microorganisms including rhizobacteria, endophytes, and mycorrhizal fungi, which are expected to be alternative fertilizers with the advantages of being cost-effective, toxin-free, and eco-friendly. - Highlights the potential use of endophytic bacteria for protecting crops against pathogens - Presents an in-depth analysis of the molecular level to understand the impact of ATP-binding cassette transporters on plant defense mechanisms with a discussion of the potential anti-pathogenic agents based on terpenes and terpenoids. The content of the book is aimed at addressing UN SDG goals 2, 12, and 15 to achieve zero hunger and responsible consumption and production, and to sustainable use of terrestrial ecosystems, respectively. This comprehensive resource is suitable for researchers, students, teachers, agriculturists, and readers in plant science, and allied disciplines.

This volume presents information about protocols for micropropagation of more than 40 species of medicinal plants. The contents combine knowledge about the scientific principles of micropropagation with state of the art updates in tissue culture techniques presented by plant scientists. The readers will learn about techniques required to grow plants in challenging conditions that aim to reduce the impacts of injudicious harvesting, deforestation, climate change, pollution, urbanization and other factors that limit the ability to meet current demand. General topics such as biotization and pharmaceutical investigation are also included to guide readers about the significance of these plants in research and development for new medicines. The book provides protocols for micropropagation of important medicinal plants like Rauvolfia serpentina, Catharanthus roseus, Withania somnifera, Tylophora indica, Bacopa monnieri, Aloe vera, Phyllanthus amarus, Allium sativum, Moringa oleifera, Operculina turpethum, Glycyrrhiza glabra, Pterocarpus marsupium, Vetiver grass, Ruta graveolens, Tinospora cordifolia, Kaempferia, Hedychium, Decalepis hamiltonii, Saraca asoca, Wrightia tinctoria, Wrightia arborea, Artemisia absinthium, Aegle marmelos, Atropa acuminata, Atropa belladonna, Alpinia species, Hedychium species, and Cissus species. This book is a handy reference for medicinal chemists, horticulturists and pharmacists who want to learn about the growth and conservation of important medicinal herbs and plants.

This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 1: - An Overview of advances in CRISPR-CAS research - Applications of CRISPR/CAS9-based genome editing for industrial microorganisms - Gut microbiome modulation to address gut dysbiosis - Bifidobacterium genome editing for probiotic development and metabolic engineering. - Insights into the use of lactic acid bacteria as starter cultures in the food - Genome editing of vegetable-derived L. Plantarum - Genome editing in Bacillus Licheniformis Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics.

Data Science for Agricultural Innovation and Productivity explores the transformation of agriculture through data-driven practices. This comprehensive book delves into the intersection of data science and farming, offering insights into the potential of big data analytics, machine learning, and IoT integration. Readers will find a wide range of topics covered in 10 chapters, including smart farming, AI applications, hydroponics, and robotics. Expert contributors, including researchers, practitioners, and academics in the fields of data science and agriculture, share their knowledge to provide readers with up-to-date insights and practical applications. The interdisciplinary emphasis of the book gives a well-rounded view of the subject. With real-world examples and case studies, this book demonstrates how data science is being successfully applied in agriculture, inspiring readers to explore new possibilities and contribute to the ongoing transformation of the agricultural sector. Sustainability and future outlook are the key themes, as the book explores how data science can promote environmentally conscious agricultural practices while addressing global food security concerns. Key Features: - Focus on data-driven agricultural practices - Comprehensive coverage of modern farming topics with an interdisciplinary perspective - Expert insights - Sustainability and future outlook -Highlights practical applications Data Science for Agricultural Innovation and Productivity is an essential resource for researchers, data scientists, farmers, agricultural technologists, students, educators, and anyone with an interest in the future of farming through data-driven agriculture.

This reference presents information about models utilized in experimental medicine and pharmaceutical research and development for several human diseases. Written by experts in immunology, cancer biology and pharmacology, the book provides readers with handy notes and updated data on animal models that are critical to research planning and lab execution. The main feature of the book is a set of 12 structured chapters that focus on a specific disease such as cancer, infectious diseases, autism, autoimmune diseases, Alzheimer’s disease and anemia. The contributors have gathered information on a wide range of genetic and physiological animal models that are employed in research with comparative charts that highlight their main differences. The book also includes chapters for special topics like food allergies and dentistry. Additional features of the book are an explanation of disease mechanisms that give an easy understanding, notes for idiopathic models and specific clinical conditions, and a list of references for advanced readers. Animal Models In Experimental Medicine is essential reading for scholars, graduate students and senior researchers in life sciences and clinical medicine. It also serves as a resource for professionals involved in bench-to-bedside pharmaceutical projects.

Research Methodology and Project Management in Biotechnology is a vital resource addressing core concepts in the dynamic field of biotechnology. This comprehensive textbook focuses on research methodology, techniques, and project management, and provides essential knowledge for students and faculty in life sciences and allied disciplines. Key features of the book include learning objectives, self-assessments and exercises, and a simple presentation (using bullet points, tables, and figures) designed to assist comprehension and retention of key information. The book is split into 5 units with 12 focused chapters: Unit I: Molecular Biology Techniques Covers various techniques used in molecular biology, including nucleic acid isolation, DNA fragmentation, PCR, DNA sequencing, and more. Unit II: Scientific Communication and Literature Introduces the process of research writing. Unit III: Biotechnology Entrepreneurship and Marketing Covers the role of funding, intellectual property rights, and regulations. Unit IV: Genomics, Proteomics, and Bioinformatics Explores DNA sequencing strategies, gene expression analysis, and the role of bioinformatics in drug discovery. Unit V: Advanced Biotechnological Techniques Covers topics such as antisense technology, molecular cytogenetics, pharmacogenomics, next-generation DNA sequencing, and ethical considerations in science and technology. Unit VI: Medical Biotechnology Covers disease detection and diagnosis, genetic diseases, personalized medicine, nanotechnology, gene therapy, regenerative medicine, and the Human Genome Project. This textbook is suitable for courses aimed to enhance biotechnology project planning and execution skills and building a professional career path in biotechnology.

Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective offers a comprehensive exploration of the dynamic field of pharmaceutical nanobiotechnology, focusing on its medical applications. This edited reference serves as a valuable resource for researchers, students, and professionals in various disciplines (pharmacology, biotechnology, clinical medicine and nanotechnology) , providing insights into the latest advancements and practical implications of nanotechnology in the pharmaceutical sector. The book presents 14 edited and referenced chapters that cover several themes for readers. General Pharmaceutical Nanobiotechnology: Introduction to the interdisciplinary field Exploration of nanoscale materials for medical purposes Nanoparticle Development and Applications: Bioinspired Nanomedicines Lipid-Based Nanocarriers Metallic Nanoparticles and Their Applications Nanoparticle Targeting Strategies Nanomedicine-Based Therapies for Cancer Stem Cells Biotechnological Aspects: Biotechnological Significance of Exosomes Glycoconjugates: Biosynthesis and Functions Innovative Nanotherapies: Novel Nanotechnological Approaches for Glioblastoma Biocompatibility of Nanomedicines and Bio Corona Diagnostic and Sensing Applications: Role of Nanoparticular/Nano Vesicular Systems as Biosensors In Vitro Applications of Drug-Carrying Nanoparticles in Cell Culture Studies In Vivo Imaging Techniques: Bioluminescence and Fluorescence Imaging Precision Medicine: The Role of Nano and Biopharmaceutics in Precision Medicine

Chemical Fingerprints of Medicinal Plant- HPTLC Profiling gives an overview of the use of high-performance thin-layer chromatography (HPTLC) for profiling medicinal herbs. Starting with an introduction to HPTLC the book guides the reader through HPTLC instrumentation and laboratory application. Additional notes on the stationary HPTLC phases and hyphenating HTPLC with other analytical techniques are also provided. The book concludes with an exhaustive list of HPTLC fingerprints of many herbs that can be used in medicinal preparations. The book outlines a scientific approach to the identification and selection of herbs for preparing traditional medications. By reading this book, learners will be able to 1) understand the basics of HPTLC, 2) learn how to use the instruments for lab analysis and 3) quickly identify chemical fingerprints of important medicinal herbs. Key Features - A concise overview of HPTLC and associated techniques - A Step-by-step guide to performing HPTLC analysis - Full color illustrations - An exhaustive list of HPTLC fingerprints for 108 medicinal plants, with botanical names - An appendix of TLC solvent systems and reagents for different phytochemical compounds and secondary metabolites - Simple language for easy understanding - Detailed bibliography Chemical Fingerprints of Medicinal Plant- HPTLC Profiling is an essential handbook for scholars in analytical chemistry, plant science and traditional medicine who want to understand the application of HPTLC techniques for research and development in phytomedicine.