Anti-Cancer Agents in Medicinal Chemistryaims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents. Each issue contains a series of timely in-depth/mini-reviews and guest-edited issues written by leaders ...read more
eISBN: 978-981-5313-23-9
ISBN: 978-981-5313-24-6
Organic Spectroscopy: Technology and Applications is an essential guide to the principles and practices of spectroscopy in organic chemistry. This comprehensive text covers the fundamentals of the electromagnetic spectrum, UV-visible, infrared (IR), Raman, nuclear magnetic resonance (NMR), and mass spectrometry, providing a structured approach to understanding each technique`s role in molecular analysis. Designed for students and professionals alike, the book emphasizes problem-solving and structural analysis, offering a methodical progression through each technique to build practical expertise. Illustrated with detailed diagrams and real-world spectra, the text also includes solved examples to reinforce learning and enhance application skills. Key Features: - Comprehensive coverage of core spectroscopy techniques: UV-visible, IR, Raman, NMR, and mass spectrometry. - Step-by-step explanations and problem-solving techniques for structural analysis. - Numerous illustrations and spectra for visual learning.
eISBN: 978-981-5256-56-7
ISBN: 978-981-5256-57-4
This book provides an in-depth and comprehensive overview of andrographolides and their analogues, highlighting their botanical origins, phytochemistry, pharmacological properties, and biotechnological applications. It explores the isolation, purification, and spectroscopic characterization of andrographolides from natural sources, emphasizing their therapeutic potential in antidiabetic studies and other medicinal uses. The book also explains cultivation techniques, agronomic strategies for Andrographis species, genetic improvements, and in vivo extraction methods aimed at enhancing andrographolide yields, with a focus on commercial cultivation and export strategies. Dedicated chapters, contributed by experts, discuss the ethnobotanical significance of Andrographis species, traditional medicinal formulations, and advanced biotechnological interventions for conservation and utilization. Recent breakthroughs in understanding andrographolides'biosynthesis, metabolism, safety aspects, and promising applications in treating diabetes, cancer, inflammation, liver diseases, and neurological disorders are also covered. Readers will gain insight into how andrographolide analogues can be developed as "lead molecules" for creating next-generation phytodrugs. Key Features - Provides a comprehensive account of andrographolide-producing plant sources and their phytochemical and pharmacological properties. - Explores the role of biotechnology in enhancing andrographolide production through in vivo and in vitro methods. - Highlights the therapeutic efficacy of andrographolides and analogues in antidiabetic, anticancer, hepatoprotective, and anti-inflammatory drug development. - Discusses cutting-edge advancements in the biosynthesis and semisynthetic derivatives of andrographolides. - Covers cultivation, agronomic techniques, and genetic improvements to optimize andrographolide production for commercial applications. This book is a valuable resource for researchers, pharmacologists, biotechnologists, and biomedical professionals focused on natural product-based drug discovery involving andrographolide.
eISBN: 978-981-5274-10-3
ISBN: 978-981-5274-11-0
Metabolites of Medicinal Plants: Insightful Approaches provides a comprehensive exploration of the bioactive compounds found in medicinal plants and their pharmacological significance. The book covers key topics such as the economics of medicinal and anticancer plants, phytochemistry, therapeutic potential, and advanced applications like nanotechnology-based drug delivery systems and CRISPR-Cas techniques. It also examines the role of these plants in combating diseases like diabetes and metabolic syndrome and their role in traditional medicine systems. This resource is essential for students, researchers, and professionals in phytochemistry, pharmacology, drug discovery, and healthcare practices. Key Features: 1. Wide range of topics from medicinal plant economics to pharmacological applications. 2. Latest discoveries in plant bioactive compounds and their therapeutic uses. 3. Novel drug delivery methods to enhance efficacy. 4. Linking genes to metabolites through advanced omics approaches.
eISBN: 978-981-5305-15-9
ISBN: 978-981-5305-16-6
2-Deoxy-D-Glucose: Chemistry and Biology extensively examine 2-deoxy-D-glucose (2DG), a glucose analog with profound biomedical and therapeutic potential. This detailed resource covers 2DG's chemical structure, methods of synthesis, and its pivotal roles in diagnostics and therapeutics. This book provides a comprehensive overview of the compound’s multifaceted uses, from antiviral applications to its emerging role in cancer treatment. Key Features: - Comprehensive coverage of 2DG synthesis, structure, and characterization. - Insights into 2DG’s diagnostic and therapeutic potential, including cancer and antiviral applications. - Exploration of its role in the Warburg effect and glycosylation inhibition. - Discussion on 2DG’s clinical applications, including COVID-19 treatments.
eISBN: 978-981-5305-78-4
ISBN: 978-981-5305-79-1
Chiral Ionic Liquids: Applications in Chemistry and Technology provide an in-depth exploration of the synthesis, design, and diverse applications of chiral ionic liquids (CILs) in modern chemistry. This comprehensive book covers fundamental concepts such as ionic liquids' structural organization and chirality, while also discussing advanced topics like enantiomeric separations, organocatalysis, and chiral recognition. Through ten detailed chapters, the book addresses carbohydrate-based CILs, CILs from amino acids and terpenoids, and their roles in capillary electrophoresis, chromatography, and spectroscopic techniques. This resource is valuable for researchers and industry professionals working in organic synthesis, materials science, and applied chemistry. Key Features: - Covers basic concepts of ionic liquids and chirality - Includes detailed methodologies for synthesizing CILs - Explores CILs in enantiomeric separations and organocatalysis - Discusses chiral recognition using spectroscopy and chromatography - Provides insights into CIL-based biphasic systems and supported ionic liquids
eISBN: 978-981-5223-88-0
ISBN: 978-981-5223-89-7
Anthocyanins are a diverse group of phytochemicals used for the treatment and management of acute and chronic ailments. This book is a comprehensive guide to anthocyanins and their importance as pharmaceutical and nutraceutical agents. The book provides detailed information about anthocyanin sources and their application in the treatment of diseases including cancer, gastric disorders, infertility, metabolic diseases, and neurological disorders. Key features · Explains the importance of phytochemicals and nutraceuticals · Provides details of anthocyanin sources and mechanisms of action · Includes chapters dedicated to the use of anthocyanins to treat specific diseases · Provides a summary of the market for anthocyanins as a pharmaceutical and nutraceutical product · Includes scientific references
eISBN: 978-981-5238-12-9
ISBN: 978-981-5238-13-6
Therapeutic Insights into Herbal Medicine through the Use of Phytomolecules offers a comprehensive exploration of the pharmacological potential of plant-derived compounds. The book provides an in-depth look at the therapeutic applications of phytomolecules in various health conditions. It begins with an analysis of bioactive phloroglucinol compounds and progresses to cover plant-based approaches for managing rheumatoid arthritis, diabetes, cancer, neurological disorders, and antiviral activity. The volume also covers the molecular mechanisms of flavonoids, the preclinical pharmacology of Indian medicinal herbs, and the neuroprotective role of andrographolide in Parkinson's disease. Designed to inform and inspire, this book is ideal for researchers, clinicians, and students interested in the therapeutic potential of natural products.
eISBN: 978-981-5305-03-6
ISBN: 978-981-5305-04-3
Computer-Aided Drug Discovery Methods: A Brief Introduction explores the cutting-edge field at the intersection of computational science and medicinal chemistry. This comprehensive volume navigates from foundational concepts to advanced methodologies, illuminating how computational tools accelerate the discovery of new therapeutics. Beginning with an overview of drug discovery principles, the book explains topics such as pharmacophore modeling, molecular dynamics simulations, and molecular docking. It discusses the application of density functional theory and the role of artificial intelligence in therapeutic development, showcasing successful case studies and innovations in COVID-19 research. Ideal for undergraduate and graduate students, as well as researchers in academia and industry, this book serves as a vital resource in understanding the complex landscape of modern drug discovery. It emphasizes the synergy between computational methods and experimental validation, shaping the future of pharmaceutical sciences toward more effective and targeted therapies.
eISBN: 978-981-5256-74-1
ISBN: 978-981-5256-75-8
The Roles and Responsibilities of Clinical Pharmacists in Hospital Settings is a comprehensive textbook designed to equip graduate pharmacy students and residents with the essential skills and knowledge needed for effective clinical pharmacy practice in hospitals. This book emphasizes the multidisciplinary nature of clinical pharmacy and the importance of adhering to international guidelines and standards. The book provides an overview of hospital pharmacy practice with an introduction to the essential requirements of a hospital environment, followed by a detailed exploration of clinical pharmacist roles across major medical subspecialties, including internal medicine, infectious diseases, intensive care, pediatrics, cardiology, and oncology. Key Features General and specialized Roles: Comprehensively covers different aspects of clinical pharmacology from basics to medical subspecialties Practical Insights: Offers practical tools, reference resources, and strategies for clinical pharmacy practice across different hospital departments. Advanced Practice: Guides readers from foundational knowledge to advanced clinical pharmacy practices, preparing them for specialized roles within hospital settings. Global Standards: Highlights the importance of multidisciplinary education and adherence to global clinical pharmacy standards. This textbook is an essential resource for pharmacy students, specialist assistants, and anyone pursuing a career in clinical pharmacy.
eISBN: 978-981-5238-54-9
ISBN: 978-981-5238-55-6
This book aims to fill research gaps in the search for chemotherapeutic and chemopreventive natural compounds. It includes a collection of detailed reviews focusing on bioactive compounds from plant sources that can be beneficial for cancer therapy. Topics covered include the role of antioxidants in cancer therapy, medicinal plants for cancer chemotherapeutics, bioactive compounds from marine plants, and a review of inhibiting nitric oxide reactions for preventing cancer. Chapters are contributed by researchers who have provided detailed lists and descriptions of the relevant plant sources, the compounds and the biochemical reactions. The book includes references for advanced reading. This book is intended as a reference for scholars and healthcare professionals studying natural medicines for cancer prevention and treatment.