Mesenchymal Stem Cells and Craniofacial Regeneration

Author(s): Jingang Xiao, Lin Liu, Lei Wang, Kui Huang, Yong Li and Zhihao Yao

DOI: 10.2174/9781681083155116010006

Craniofacial Defects and their Regeneration: Destruction and Regeneration of the Periodontium, Craniofacial Tumors, Trauma, and Congenital Defects

Pp: 90-230 (141)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Injuries in the cranial and maxillofacial region are clinically important because this region contains the most exposed parts of the body and is important for expression of social etiquette. Currently, the most common methods used to repair cranial and maxillofacial defects are autologous tissue transplantation and artificial composite material reparation. However, these methods have limitations. In recent years, tissue engineering has been developed as an alternative method of craniofacial reparation and reconstruction. Stem cell therapy is an emerging strategy that may potentially be used for the reconstruction of craniofacial defects.

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