Polarity Index in Proteins-A Bioinformatics Tool

Author(s): Carlos Polanco

DOI: 10.2174/9781681082691116010010

Pathogenic Bacteria

Pp: 36-49 (14)

Buy Chapters

* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

This chapter includes the identification of a group of peptides known as antimicrobial peptides. They have an important role in the immune system of all living organisms. The identification of the main function associated to each peptide was made by calculating the polar profile of the peptide with the QSAR method called polarity index, already described in Sect. 3.3. The peptides computationally tested were taken from two different databases: Antimicrobial Peptides Database (APD2), and Uniprot Database, which included the set of peptides called selective cationic amphipatic antibacterial peptides.

Recommended Chapters

We recommend

Favorable 70-S: Investigation Branching Arrow

Authors:Bentham Science Books