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SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
The prognosis of malignant pleural mesothelioma remains very poor. The role of the two intentionally-curative surgical procedures, extra-pleural pneumonectomy and radical pleurectomy/decortication, is widely debated and mainly focused on the impact on survival, which is not significantly improved whatever the operation may be.
On these bases the clinical impact of these procedures may assume a relevant importance on immunology, symptoms and quality of life.
Despite the unsatisfactory results on survival these two procedures proved effective in ameliorating symptoms and quality of life. In the early-postoperative period, greater improvements are detected after pleurectomy/decortication, whereas extrapleural pneumonectomy produced better symptom-relief later. Conversely this procedure may have a negative impact on immunological conditions thus producing a significantly greater risk of postoperative infection implying a higher morbidity rate.
Keywords:
Extrapleural pneumonectomy, immunology, pleurectomy/decortication, quality of life, thoracic surgery.
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Authors:Bentham Science Books