Calixarenes in Biotechnology and Bio-Medical Research

Pp: 206-301 (96)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Application of calixarene derivatives in biotechnology and bio-medical researches is reviewed in this article. Results on antiviral, bactericidal, antithrombothic, antituberculosis, anticancer activities of modified calixarenes are presented. Transfection ability, specific protein complexation, enzyme mimic, membranotropic properties and toxicity of modified calixarenes are described.

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