Women’s Heart and Estrogens

Author(s): Genovefa D. Kolovou

DOI: 10.2174/9781681081120115010003

Estrogens and Atherogenesis

Pp: 3-30 (28)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

In the 21st century, cardiovascular disease has become a global cause of morbidity and a main contributor to mortality in most countries, regardless of the important actions which have been endorsed for primary and secondary prevention. Concerning women's cardiovascular mortality, in all age groups it is more frequent and even greater than it is due to breast cancer. In this chapter, the stages of atherogenesis, the factors that induce atherogenesis (environmental and genetic), the effects of estrogens on the stages of atherogenesis, and finally, the effects of estrogens on those components will be analyzed.

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