Next-Generation Sequencing and Sequence Data Analysis

Author(s): Kuo Ping Chiu

DOI: 10.2174/9781681080925115010017

ChIP-EM Libraries

Pp: 112-116 (5)

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  • * (Excluding Mailing and Handling)

Next-Generation Sequencing and Sequence Data Analysis

ChIP-EM Libraries

Author(s): Kuo Ping Chiu

Pp: 112-116 (5)

DOI: 10.2174/9781681080925115010017

* (Excluding Mailing and Handling)

Abstract

Epigenetic modifications (EMs) refer to the external modifications on DNA that do not alter coding specificity. EMs include DNA methylations (DMs) and histone modifications (HMs). This chapter will focus on HMs. We will discuss how ChIP-EM libraries can be made and what can be expected from the sequence data analysis. There are many laboratories working in this field and many reports have been published. Readers are recommended to consult the previous reports for further understanding of this subject.


Keywords: Chromatin immunoprecipitation, ChIP, EM, Epigenetic modifications.

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