Nanomedicine for Delivery of Drugs in Breast Cancer: Recent Advances and Prospects

Pp: 108-160 (53)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Breast cancer is one of the most invasive cancers, with a high mortality rate; almost all treatment options are invasive, with significant side effects, and not always curative. Nanomedicine, the application of nanotechnology to medicine, is an interesting approach to improving the delivery of anticancer drugs, thus increasing their therapeutic index and specificity, while reducing side effects. This chapter describe the most widely studied nanoparticulate drug delivery systems, also discussing nanocarriers in clinics and recent advances in targeted drug delivery approaches for breast cancer treatment.

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