Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Hydroxyapatite (HA) is the main mineral constituent of human bones. HA nanocrystals can be synthesized using a variety of wet solution methods including chemical precipitation, hydrothermal, sol-gel, micro- and nano-emulsion. HA nanocrystals synthesized from the chemical precipitation process generally exhibit plate-like morphology. They tend to self-organize into an ordered structure in the presence of biopolymers. The self-assembled HA-polymer nanocomposites simulate the hierarchical structure of human bone at a fundamental level. Such biomimetic nanocomposites favor osteoblast adhesion and proliferation, thereby stimulating new bone growth. Proper understanding of the biomineralization of self-assembled structures is needed for designing high performance polymer nanocomposites in bone tissue engineering.
Keywords:
Bone, hydroxyapatite, nanocrystal, polymer, precipitation, self-assembly, biocompatibility, biomimetic structure, scaffold, electrospinning
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Authors:Bentham Science Books