Tuberculosis Treatment: The Search For New Drugs

Author(s): Marcus V.N. de Souza

DOI: 10.2174/9781608057887113010004

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Important Historical Facts of Tuberculosis Treatment and Drug Development

Pp: 3-37 (35)

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Abstract

In this chapter will be highlight some important historical facts of tuberculosis treatment and drug development, such as theories, studies and treatment of TB between 17-20th Century, historical aspects of TB drug discovery, side effects, fixed-dose combinations, causes of the resurgence of TB, AIDS, multi-drug-resistant tuberculosis (MDR TB) and extensive-drug- resistant (XDR).

Keywords:

Tuberculosis, Mycobacterium tuberculosis, drugs, treatment, fixeddose combinations, multi-drug-resistant tuberculosis (MDR TB), extensive-drugresistant tuberculosis (XDR TB), natural products, synthesis, AIDS, theories, historical aspects.

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