Dynamics of Biological Macromolecules by Neutron Scattering

Author(s): Antonio Deriu, Maria Teresa Di Bari, Yuri Gerelli

DOI: 10.2174/978160805219611101010079

Sugar - Lipid Interactions: Structural and Dynamic Effects

Pp: 79-84 (6)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Sugar-lipid complexes are nowadays extensively applied in biology, medicine and food science. In particular, sugars play an important role in maintaining cell viability in stressful environmental conditions. A detailed understanding of lipid-saccharide-solvent interactions can be achieved by a combined use of advanced microscopic structural and dynamical investigation techniques. In this review the effect of saccharide content on the gel to liquid-crystalline phase transition and on the multilayer structure of lipid membranes, as well as on the aggregation properties of liposomes in colloidal systems, is discussed.

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