Frontiers Between Science and Clinic in Odontology Volume Title: Phosphorylated Extracellular Matrix Proteins of Bone and Dentin

Author(s): Adele L. Boskey

DOI: 10.2174/978160805465711202010380

In Vitro and In Vivo Regulation of Mineral Crystal Size and Shape

Pp: 380-400 (21)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Hydroxyapatite crystals formed in various tissues throughout the body have very specific shapes and sizes. These sizes, though heterogeneous, are specific to the tissue type and the age of the animal from which the crystals were derived. A multitude of factors contribute to the regulation of crystal sizes in different tissues. This chapter reviews those factors, and presents a brief introduction to the science of nucleation and crystal growth that governs the ways these crystals form and proliferate.

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