Sperm-Mediated Gene Transfer: Concepts and Controversies

Author(s): Kevin R. Smith

DOI: 10.2174/978160805237011201010125

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Conclusions

Pp: 125-130 (6)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Several experts in the various fields of SMGT have contributed valuable knowledge to this eBook. This chapter offers a synthesis of the key concepts covered throughout the book, and critically evaluates the current status and controversial aspects of SMGT.

Keywords:

Augmented uptake, Autouptake, En masse GM, Episomal transgene, Gene targeting, Germline modification, Horizontal inheritance, Human artificial chromosome, SMGT scepticism, Zinc-finger nuclease.

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