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SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Ammonia is thought to play a significant role in the development of hepatic encephalopathy (HE) in patients with liver failure. Some of the key questions have been whether there is an abnormal permeability surface-area product across the blood-brain barrier (PSBBB) for ammonia in patients with cirrhosis and whether the cerebral metabolic rate of ammonia is altered. In this chapter, we discuss how functional molecular imaging using positron emission tomography (PET) can be utilized for in vivo studies of cerebral ammonia kinetics and what the studies so far have shown.
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Authors:Bentham Science Books