Antibodies Applications and New Developments

Author(s): William Graham Wood

DOI: 10.2174/978160805264611201010014

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The Discovery and Development of the Antigen-Antibody Reaction Part 2: Commercial Immunoassay Development and Applications

Pp: 14-28 (15)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

The second chapter continues the history of immunoassay and mainly deals with the commercialization and automation of immunoassays, the impact of monoclonal antibodies and their potential role in standardization and the continued development towards microformats and multianalyte immunoassays.

This chapter also includes the terminology used in immunoassays and schematic representation of assay design in the form of diagrams, as well as a brief look into the possible future development of immunoassay techniques and their application and impact in clinical in vitro diagnostic procedures.

Keywords:

Antibody, Immunoassay, Design, Labelling

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