Preclinical Atherosclerosis, Global Cardiovascular Risk and Cardiovascular Events

Author(s): S. Novo, G.R. Amoroso, F. Bonura, P. Carità, E. Corrado and G. Novo

DOI: 10.2174/978160805221911201010022

From Risk Factors to Algorithms of Risk and Cardiovascular Risk Charts

Pp: 22-28 (7)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

The GCVR aims to stratify subjects without past history of CVD for their risk to develop CVE in the following ten years. The GCVR can be assessed through "risk charts” or electronic calculators that provide an individual score. The results indicate an absolute risk or a relative risk. Various countries use different systems in order to respect the different populations of reference. In particular, the Framingham equations have effectiveness in calculating CV risk in middle-aged Americans or Afro-American subjects. The "European charts" is a specific method for subjects belonging to "high risk" (the Northern Europe) or “low risk" (Mediterranean) European countries. Finally, the “Progetto Cuore” aims at estimating the risk in the Italian population. The Progetto Cuore’s equation is available for free on the website (www.cuore.iss.it.).

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