Contemporary Sleep Medicine For Patients

Author(s): Stephen W. Littleton, Babak Mokhlesi

DOI: 10.2174/978160805267711101010027

Obesity Hypoventilation Syndrome

Pp: 27-28 (2)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Obesity Hypoventilation syndrome (OHS) is defined as the triad of obesity, daytime carbon dioxide accumulation (hypoventilation), and sleep disordered breathing in the absence of an alternative explanation. Patients with obstructive sleep apnea (OSA), those who are more obese and have more severe OSA are more likely to have the syndrome. It is unclear why some patients with OSA develop OHS and others do not. It is important to identify the syndrome early, as these patients may have a significantly increased risk of dying if left untreated. The authors describe current understanding of the pathogenesis of the disorder and optimal treatment modalities.

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