The Regulatory Mechanism Targeting Microglia

Microglia are vital immune cells in the central nervous system (CNS) responsible for maintaining brain balance and responding to injuries or infections. They are regulated by a variety of mechanisms involving interactions with different signaling molecules and cell types within the CNS. Ensuring proper regulation of microglial activity is essential for preserving brain health and preventing the onset of neuroinflammatory and neurodegenerative disorders.

Keywords: Anti-inflammation, Microglia activation, Microglial phenotype, Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2), Pro-inflammation, Phagocytosis, Toll-like receptors (TLRs).