The Role of Cerebrospinal Fluid in the Clearance System

Pp: 90-93 (4)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

The cerebrospinal fluid (CSF) system is vital for maintaining the brain's environment and clearing waste. The BBB-CSF barriers regulate the movement of molecules between the blood and brain fluids. CSF flow is driven by arterial pulsation and may be influenced by vascular muscle. The glymphatic system helps drain interstitial fluid, especially during sleep. Anesthesia may impair CSF circulation, affecting brain waste clearance. Meningeal lymphatic vessels also assist in CSF clearance and immune cell movement. Understanding these processes can lead to new treatments for neurological disorders.

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Authors:Bentham Science Books