Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Andrographis paniculata (AP) is a traditional herb known as “king of bitters” and belongs to Acanthaceae. This plant is used traditionally to treat fever, sore throat, snake bites, and upper respiratory tract infections. The pharmacological effects exhibited by AP are actually due to the presence of several classes of phytocompounds. Among the numerous bioactive compounds generated by Androgrpahis paniculata, Andrographolide (AG) is the primary active phytochemical. This compound shows various biological functions, such as anti-inflammatory, anticancer, antimicrobial, neuroprotective, cardioprotective, and organ- and bone-protective activities. On the other hand, AG's structural analogs also showed various potent biological effects against different kinds of dreadful diseases. Hence, it is noteworthy to summarize the various pharmacological effects of AG and its analogs to help the researchers focus on this area. Therefore, in this chapter, we elaborated on various biological functions of AG and its derivatives; this review would be a standalone reference for AG's bioactives and analogs.
Keywords:
Andrographolide, Analogs, Andrographis paniculata, Bioactive compounds, Pharmacological activities
We recommend
Authors:Bentham Science Books