Polymers in Controlled Drug Delivery

Pp: 101-139 (39)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

This book chapter explores the multifaceted role of polymers in the field of controlled drug delivery, providing a comprehensive overview of the latest advancements and applications. Polymers have emerged as pivotal components in designing drug delivery systems due to their tunable properties, biocompatibility, and ability to modulate drug release kinetics. The chapter delves into the various types of polymers employed in controlled drug delivery, including natural, synthetic, and hybrid polymers, highlighting their unique characteristics and functionalities. The discussion encompasses the design principles behind polymer-based drug delivery systems, elucidating how factors such as molecular weight, architecture, and composition influence drug release profiles. Additionally, the chapter scrutinizes the diverse strategies employed to achieve controlled drug delivery, such as micelles, nanoparticles, and hydrogels, each offering tailored solutions for specific therapeutic needs. Special emphasis is placed on the biodegradability and biocompatibility of polymers, ensuring safety and efficacy in clinical applications. Through a critical examination of recent research and case studies, this chapter provides valuable insights for researchers, practitioners, and students in the pharmaceutical and biomaterials fields. It serves as a comprehensive resource for understanding the pivotal role of polymers in advancing controlled drug delivery technologies, ultimately contributing to the evolution of more efficient and patient-friendly therapeutic interventions.

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Authors:Bentham Science Books