Metal Complexes: Environmental and Biomedical Applications

Author(s): Rojalin Sahu* and Puspanjali Sahu * .

DOI: 10.2174/9789815238723124010010

Antibacterial and Antifungal Applications of Metal Complexes

Pp: 126-144 (19)

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* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Metal ions have an extremely important role in preserving the longevity of living organisms. Humans can suffer from a variety of health issues when particular metal ions are deficient, including growth retardation from a zinc deficiency in the diet, pernicious anemia from an iron deficiency, and infantile heart disease from a copper deficiency. Antibiotic resistance is becoming more severe every day, posing a growing risk to public health. The creation of innovative medications with improved efficacy and new mechanisms of action is urgently needed in this situation. Inorganic compounds, specifically metal complexes, have a significant role in novel metal-based drug development. Owing to the inclination of the scientific community towards designing new metal complexes as diagnostic agents and drugs, a new branch of chemistry was developed, which is known as inorganic medicinal chemistry. In this chapter, metal complexes used as anti-fungal and anti-bacterial agents are discussed.

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