Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
This chapter deals with the approved and marketed anticancer drugs derived
from marine sponges, mollusks/cyanobacteria, and tunicates; marine biota-derived
anticancer compounds in clinical trials i.e in III, II, and I phases; and bioactive new
chemical entities (NCEs) with anticancer function from marine biota. Limiting factors
in the development and approval of drugs from marine biota and significant challenges
in the development and approval of marine drugs are also given.
Keywords:
Challenges in drug development, Clinical trials, Marine anticancer drugs, New chemical entities, Limiting factors.
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Authors:Bentham Science Books