Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Silymarin is obtained from the seeds of the herb Silybum marianum (milk
thistle) belonging to the family Carduus marianum. The herb is traditionally used as a
liver tonic and in biliary tract disease treatment, dysmenorrhea, and varicose veins. The
major bioactive constituents of Silymarin are silychristin, silybin A, silybin B,
isosilybin A, and isosilybin B, while other flavonolignans such as neosilyhermin,
silyhermin, and silydianin are also present. Due to its cytoprotective anti-inflammatory,
and antifibrotic action, it is the most acceptable and safe natural compound in the
treatment of hepatic diseases like jaundice, liver cirrhosis, and chronic viral hepatitis.
Silymarin functions as a free radical scavenger and modifies the activity of enzymes
that cause cellular damage, fibrosis, and cirrhosis to occur. In the present book chapter,
the author will explore the potential of the herb in the treatment of hepatic diseases.
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Authors:Bentham Science Books