Emerging Approaches to Tackle Neglected Diseases: From Molecule to End Product

Author(s): Himani Bajaj, Sindhu Agarwal*, Anjali Sharma, Mayank Yadav and Md. Arif Naseer

DOI: 10.2174/9789815196863124010011

Current Therapeutic Strategies for Trachoma

Pp: 182-199 (18)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

As a result of persistent follicular conjunctivitis brought on by Chlamydia trachomatis and consequent corneal scarring, about 6 million people have irreparable blindness. Chlamydia trachomatis is a bacterium that causes trachoma, an eye infection. Early signs include eyelid itchiness and irritation, whereas advanced signs include swollen eyelids, pus oozing from the eyes, photophobia (light sensitivity), discomfort in the eye, and vision issues. Using the SAFE strategy, the WHO is driving an international campaign to eradicate Blinding Trachoma. Trichiasis surgery, antibiotic treatment for infection, hygiene promotion on the face, and environmental changes to improve air quality are all part of this. The best antibacterial medication for widespread distribution is oral azithromycin.

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