Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Asthma in children is associated with serious exacerbations that are
modulated by inflammation. The expression of inflammatory cytokines varies
according to the severity of the disease. The transition from the state of exacerbation of
the disease to the state of cure always passes through a relationship between
inflammatory and anti-inflammatory mediators. This study looks at the expression of
IL-38 and NLRP3 inflammasome in severe childhood asthma. NLRP3 inflammasome
is upregulated in severe asthma, contrasting with low levels of IL-38. The
inflammatory pattern of severe asthma in children is characterized by the expression of
IL-17, IL-32, IL-1β, and NLRP3 inflammasome.
Keywords:
ELISA, Gene expression, Induced sputum, Immunity, Severe asthma.
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Authors:Bentham Science Books