Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
When NPs are included in a Biological environment, they associate with a
large number of circulating proteins. As a result, they interact dynamically with each
other. This structure, which is defined as PC, affects the physical parameters of NPs
and causes positive or negative effects on them. PC composition is affected by many
properties of NPs, such as size, shape, and surface charge. Therefore, various surface
modifications on NPs directly affect PC formation and nature. Although many studies
have been carried out to understand the formation and composition of the resulting PC
structure, this area still maintains its popularity as a research topic. This review aims to
briefly give an idea about the effect of proteins in metabolism on NPs designed as
carrier molecules, the determination of these protein structures and the final fate of NPs
after PC formation.
Keywords:
Atomic force microscopy, Biocompatibility, Differential centrifugal sedimentation, Dynamic light scattering, Fluorescence correlation spectroscopy, Hard corona, Isothermal titration calorimetry, Nanomaterial shape, Nanoparticle, Nanoparticle application, Protein adsorption, Protein corona, Protein corona characterization, Protein corona dispersion, Protein corona stability, Protein corona formation, Small-angle X-ray scattering, Soft corona, Transmission electron microscopy, UV-visible spectroscopy.
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Authors:Bentham Science Books