Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective

Author(s): Bakiye Goker Bagca and Cigir Biray Avci * .

DOI: 10.2174/9789815179422123080012

Novel Nanotechnological Therapy Approaches to Glioblastoma

Pp: 274-295 (22)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Glioblastoma is one of the most aggressive and deadly types of cancer. The blood-brain barrier is the biggest obstacle to overcome in glioblastoma treatment. Nanomedicine, which describes the use of nanostructures in medicine, has significant potential for glioblastoma. Nanomedicine provides advantages in crossing the blood-brain barrier, increasing the amount and effectiveness of drugs reaching the cancer site, monitoring diagnosis and treatment through imaging agents, and increasing the effectiveness of treatments in combination applications. This chapter reviews current nanotechnology research in glioblastoma over the past few years. 

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