Natural Products for Skin Diseases: A Treasure Trove for Dermatologic Therapy

Author(s): Ali Raza Ishaq*, Tahira Younis, Tahira Akbar, Muhammad Asad Mangat, Maliha Fatima and Dongbo Cai

DOI: 10.2174/9789815179668123010005

How to Protect Your Skin from Harmful Radiation

Pp: 1-59 (59)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Our interaction with the sun is still equivocal, to say the least. We like its soothing influence on the body and soul, but we are afraid of its highly hazardous heating ability and the long-term skin damage that can emerge from chronic sun exposure. Scientists are consistently seeking to enhance sunblock products in accordance with a need for better skin protection from the sun. Once human skin is exposed to solar ultraviolet radiation (UVR), the synthesis of reactive oxygen species (ROS) skyrockets. The influx of ROS leads to oxidative stress by mutating the natural equilibrium toward a pro-oxidative state. Alteration in proteins and lipids, stimulation of inflammation, immunodeficiency, DNA damage, and activation of signaling pathways that influence gene transcription, cell cycle, proliferation, and apoptosis are all illustrations of the detrimental effects of oxidative stress. This chapter provides new insight into several Phyto-products having an antioxidant activity to suppress the UV rays impact, the relationship between UVR-aging, current understanding of the regulation of constitutive human skin pigmentation and responses to UV radiation, with emphasis on physiological factors that influence those processes.

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