Recent Advances in the Application of Marine Natural Products as Antimicrobial Agents

Author(s): Alwar Ramanujam Padmavathi*, Dhamodharan Bakkiyaraj and Sathya Narayanan Gokul

DOI: 10.2174/9789815080148123030020

Recent Update on the Patents of Antimicrobial Marine Natural Products

Pp: 389-408 (20)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Marine environment has long been shown as the source of diverse organisms and niche for numerous bioactive agents. Marine natural products are of recent interest attributing to their novelty and abundant potential in the field of medicine as well as others. In spite of this recent attention, the marine environment still exists as an under-explored and untapped resource for bioactive agents, highlighting the presence of plentiful opportunities. Bioactive molecules of marine origin have been frequently reported from the microorganisms associated with marine sediments, seawater, coral and its mucus; higher-order marine organisms, mangroves, sponges, seaweeds and sea grasses, etc. Last decade has shown copious publications reporting the bioactive potentials of marine natural products such as antimicrobial, antiviral, antiparasitic, anticancer, antioxidant, anti-inflammatory and anti-infective properties. Recent studies have also opened an avenue in marine natural product research where the discovered natural products are chemically modified to attain increased bioactivity. Such modified or altered marine natural products were of great demand in pharmaceutical, food, cosmetic and chemical industries, and hence protected by product and process patents. This chapter summarizes the intellectual property rights in the form of patents protecting marine natural products with antimicrobial potentials, including antibacterial, antifungal and antibiofilm activities. This chapter also highlights the patents and applications of modified or semi-synthetic agents related to marine natural sources with antimicrobial properties.

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