Chapter - Nanofibers Approach for Gastro Retentive Cancer | Bentham Science

Role of Nanotechnology in Cancer Therapy

Author(s): Anand J. Patel*, Bhavin R. Patel and Pranav Shah

DOI: 10.2174/9789815079999123010012

Nanofibers Approach for Gastro Retentive Cancer

Pp: 237-254 (18)

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Role of Nanotechnology in Cancer Therapy

Nanofibers Approach for Gastro Retentive Cancer

Author(s): Anand J. Patel*, Bhavin R. Patel and Pranav Shah

Pp: 237-254 (18)

DOI: 10.2174/9789815079999123010012

* (Excluding Mailing and Handling)

Abstract

Gastric cancer is the world's second leading cause of cancer-related death. Due to inadequate drug release and limited residence time at the absorption site, traditional oral dose forms have poor/low bioavailability. GRDDS is particularly useful for increasing the bioavailability of medications with a narrow absorption window in the gastrointestinal tract and for treating local diseases. Polymeric nanofibers have sparked a lot of attention among the numerous nanomaterials used in high-tech applications because of their simplicity of production, controlled size/shape, and characteristics. Filtration, barrier fabrics, wipes, personal care, and biological and pharmaceutical applications have been intensively researched with polymeric nanofibers. Electrospun polymeric nanofibers have recently been demonstrated to be a promising approach for drug delivery systems. The nanofiber method allows for stomach-specific drug release for a more extended period and improves local drug action due to the drug's extended contact time with the gastric mucosa. As a result, nanofiber technology appears to be a promising strategy for gastric retention drug delivery systems. 

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      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:63
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      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1464
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      • 11. app/Models/ContentAccess.php:647
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      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1517
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
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      520μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
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      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1548
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      • 13. app/Models/Banner.php:189
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='0b1ce139e274d1d21bf77b2bc776dd4c'
      190μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._main_menu:13
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
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        uc_cart_id
        0b1ce139e274d1d21bf77b2bc776dd4c
        _previous
        array:1 [ "url" => "https://beta.benthamscience.com/chapter/20155" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
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        status_code
        200
        
        status_text
        OK
        format
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        content_type
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        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
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        request_cookies
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        response_headers
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        ClearShow all
        Date ↕MethodURLData
        #12024-12-23 10:48:46GET/chapter/20155111172