Steroids and their Medicinal Potential

Author(s): Tabassum Siddiqui*, Asna Khan and Arfeen Iqbal

DOI: 10.2174/789815049336123010012

Spectroscopic Analysis of Steroids

Pp: 212-285 (74)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

All the steroids are basically made of seventeen carbon atom skeletons bonded in four fused rings: three six-membered cyclohexane rings and one fivemembered cyclopentane ring, they vary from each other by having different functional groups. Recent modifications have added heteroatoms like nitrogen, oxygen, sulphur, selenium, etc in the basic structure of naturally occurring steroids. Heterocyclic steroids have always been a field of interest for researchers due to their diverse biological performances. The biological activity of steroids and heterocyclic steroids is based on the structure they possess. Spectroscopy plays a key role in the determination of distinct properties of numerous compounds by their interaction with electromagnetic radiation and the sort of interactions that may occur in different regions. The structure of different steroids and heterocyclic steroids may be established through various spectroscopic techniques viz. Infrared spectroscopy (IR), Nuclear Magnetic Spectroscopy (NMR), Ultraviolet spectroscopy (UV) and mass spectrometry (MS). 

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