Steroids and their Medicinal Potential

Author(s): Aneesa Muzaffar*, Umaiya Muzaffar and Rakesh Donepudi

DOI: 10.2174/789815049336123010005

Synthesis of Steroids

Pp: 59-83 (25)

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* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

 The term steroid pertains to a broad spectrum of molecules with varying physiological roles. More explicitly, they are a class of compounds that are naturally produced in the body of living organisms as well synthetic or semi-synthetic molecules. They have tremendous effects on biochemical processes and thus any aberration from the required physiological range can have potential effects. Moreover, due to the therapeutic potential of steroids for the treatment of a wide range of diseases, many synthetic approaches have been made available to the organic chemist for their synthesis. Most of the steroids that are in use as drugs are still prepared by modifying naturally occurring steroids (partial synthesis). This chapter highlights the biosynthetic pathways of steroids and the approaches to chemically synthesize them because of their biological and synthetic relevance. 

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