Frontiers in Natural Product Chemistry

Author(s): U.L.B. Jayasinghe and Y. Fujimoto

DOI: 10.2174/978160805212710501010193

Search for Biologically Active Compounds from Sri Lankan Plants

Pp: 193-200 (8)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

In a continuation of our studies towards the discovery of biologically active compounds from Sri Lankan plants, recently we have chemically investigated the various parts of Diploclisia glaucescens (Menispermaceae), Filicium decipiens, Pometia eximia (Sapindaceae), Artocarpus nobilis (Moraceae) and Bridelia retusa (Euphorbiaceae). These work led to the isolation of a number of ecdysones, triterpenes, saponins, chalcones, stilbenes, flavonoids including over twenty-five new natural products. Some of these compounds showed high molluscicidal, insecticidal, antifungal activities and radical scavenging properties towards DPPH.

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