Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

Author(s): Simin Sharifi, Mahdieh Alipour, Atefeh Abedi, Yalda Rahbar Saadat and Solmaz Maleki Dizaj * .

DOI: 10.2174/9789815079692123010010

Advances in Dentistry Nanopharmacology

Pp: 168-194 (27)

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  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Nanotechnology has been widely used in medicine to improve the therapeutic results of various diseases. Much effort has been focused on developing new nanoparticles and determining the physicochemical properties of nanoparticles in relation to their biological fate and performance. Today, nanotechnology has been able to offer effective treatments for use in dentistry. However, in the design and evaluation of these nanotechnology-based drug delivery systems in dentistry, less attention has been paid to the pharmacology of delivered drugs and their pathophysiology. In this chapter, we discuss some recent advances in nanotechnology for drug delivery in dentistry for demineralization, osseointegration of dental implants, the treatment of oral cancer, pain management of dental pulp, and the anti-inflammatory and antimicrobial formulations as well as the role of nanopharmacology in preventive dentistry.

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