Potential Health Benefits of Biologically Active Peptides Derived from Underutilized Grains: Recent Advances in their Isolation, Identification, Bioactivity and Molecular Analysis

Author(s): Luis Jorge Coronado-Cáceres, Sergio de Jesus Calva-Estrada and Eugenia Lugo-Cervantes * .

DOI: 10.2174/9789815123340123040015

Biologically Active Peptides from Cocoa Bean (Theobroma cacao L.)

Pp: 191-204 (14)

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  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Recently, proteins and peptides have become important ingredients in functional foods due to the emergence of knowledge about their properties and biological activities. Many biologically active peptides (BAPs) have been studied from different animal and vegetal origins, principally legumes, such as soybeans and beans. BAPs have been shown to have anticancer, antitumoral, antioxidant and antimutagenic activities. Cacao, an ancient crop that originated in the Mesoamerican region, contains several bioactive compounds, e.g., polyphenols, alkaloids, flavanols, procyanidins and peptides. Cocoa beans contain 50% lipids and 14% protein, with albumins and globulins prevailing. The principal amino acids from cocoa protein are lysine, arginine, serine, proline, alanine, leucine, valine and methionine, and they allow the elucidation of the peptide’s bioactivity. Cocoa BAPs show antitumoral, antioxidant, antihypertensive and antidiabetic activities and obesity prevention. This work demonstrates the potential of all its BAPs.

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