Abstract

Diabetes Mellitus and obesity, now coined as “Diabesity”, is a worldwide epidemic that imposes a huge burden on healthcare and society. Diabesity has been associated with poor outcomes and increased morbidity and mortality. The kidneys are a vulnerable target of diabesity. In this chapter, we discuss the epidemiology, pathophysiology, and treatment of diabesity–induced kidney disease. We specifically focus on the therapeutic targets and pharmacological management of diabesity-related kidney diseases.